Rapid reconstitution of Epstein-Barr virus-specific T lymphocytes following allogeneic stem cell transplantation.
Marshall N, Howe J, Formica R, Krause D, Wagner J, Berliner N, Crouch J, Pilip I, Cooper D, Blazar B, Seropian S, Pamer E. Rapid reconstitution of Epstein-Barr virus-specific T lymphocytes following allogeneic stem cell transplantation. Blood 2000, 96: 2814-21. PMID: 11023516, DOI: 10.1182/blood.v96.8.2814.h8002814_2814_2821.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntigen PresentationAntigens, ViralBeta 2-MicroglobulinBiopolymersCD8-Positive T-LymphocytesChildEpstein-Barr Virus InfectionsFeasibility StudiesFemaleGraft SurvivalHematologic NeoplasmsHematopoietic Stem Cell TransplantationHerpesvirus 4, HumanHistocompatibility TestingHLA-A2 AntigenHLA-B7 AntigenHLA-B8 AntigenHumansKidney TransplantationLymphoproliferative DisordersMacromolecular SubstancesMaleMiddle AgedTissue DonorsT-Lymphocyte SubsetsTransplantation ConditioningTransplantation, HomologousViral LoadConceptsEBV-specific T cellsStem cell transplantationT cellsAllo-PBSCTEBV peptidesCell transplantationT lymphocytesAllogeneic peripheral blood stem cell transplantationEpstein-Barr virus–specific T lymphocytesHuman leukocyte antigen (HLA) class I tetramersEBV-specific CD8 T cellsPeripheral blood stem cell transplantationSpecific CD8 T lymphocytesUnrelated cord blood transplantationVirus-specific T lymphocytesBlood stem cell transplantationAllogeneic stem cell transplantationCD8 T cell repertoireAllo-PBSCT patientsEBV genome copiesEpstein-Barr viremiaCD8 T lymphocytesClass I tetramersCord blood transplantationPathogen-specific immunity