Featured Publications
EM reconstruction algorithms for emission and transmission tomography.
Lange K, Carson R. EM reconstruction algorithms for emission and transmission tomography. Journal Of Computer Assisted Tomography 1984, 8: 306-16. PMID: 6608535.Peer-Reviewed Original ResearchConceptsEM algorithmGood physical modelTransmission image reconstructionTransmission tomographyMaximum likelihood estimatesAlgebraic schemeRelevant physical featuresNon-negativity constraintsGlobal convergenceIterative techniquePoisson natureLikelihood estimatesParameter estimatesCounting noiseMaximum likelihoodDetector geometryPhysical modelAccurate incorporationEM reconstruction algorithmPhysical featuresSpecific algorithmsImage reconstructionAlgorithmReconstruction algorithmActual reconstruction
2020
Data-Driven Motion Detection and Event-by-Event Correction for Brain PET: Comparison with Vicra
Lu Y, Naganawa M, Toyonaga T, Gallezot JD, Fontaine K, Ren S, Revilla EM, Mulnix T, Carson RE. Data-Driven Motion Detection and Event-by-Event Correction for Brain PET: Comparison with Vicra. Journal Of Nuclear Medicine 2020, 61: 1397-1403. PMID: 32005770, PMCID: PMC7456171, DOI: 10.2967/jnumed.119.235515.Peer-Reviewed Original ResearchConceptsData-driven algorithmMotion correction methodMotion tracking informationHead motionCentroid of distributionMotion-compensated reconstructionLarge head motionsMotion correction frameworkUser-defined thresholdPET raw dataDynamic datasetsTracking informationImage registrationMotion detectionRaw dataSuch time pointsImage qualityBetter performanceMotion correctionAlgorithmLine of responseCorrection frameworkBrain PET studiesCentral coordinatesTracer kinetic modeling
2004
Software Architecture of the MOLAR-HRRT Reconstruction Engine
Johnson C, Thada S, Rodriguez M, Zhao Y, Iano-Fletcher A, Liow J, Barker W, Martino R, Carson R. Software Architecture of the MOLAR-HRRT Reconstruction Engine. 2004, 6: 3956-3960. DOI: 10.1109/nssmic.2004.1466744.Peer-Reviewed Original ResearchList-mode algorithmsDistance-based approximationCritical design goalLOR spaceSoftware architectureReconstruction engineComponent architectureEvent packetsList-mode dataRandomized approachDesign goalsImage resolutionPossible LORsPET reconstructionIterative PET reconstructionSensitivity imageComplete systemImage noiseScan framesArchitectureECAT HRRTImagesComplete computationPacketsAlgorithm
1995
A system for the 3D reconstruction of retracted-septa PET data using the EM algorithm
Johnson C, Yan Y, Carson R, Martino R, Daube-Witherspoon M. A system for the 3D reconstruction of retracted-septa PET data using the EM algorithm. 1995, 3: 1325-1329 vol.3. DOI: 10.1109/nssmic.1994.474573.Peer-Reviewed Original ResearchIntel iPSC/860 parallel computerData compression schemeImage indexingCompute nodesCompression schemeParallel algorithmParallel computersEM reconstruction algorithmStorage costComputational performanceGE Advance scannerAsynchronous readReconstruction softwareReconstruction algorithmAlgorithmLookup tableProjection dataSoftwareEM algorithmPET dataIndexingProcessorsComputerExtensive useScanner