2022
Voided Volume for Assessment of Bladder Emptying After Female Pelvic Floor Surgery: A Randomized Controlled Trial
Popiel P, Getaneh F, Yeh J, Rickey L, Bercik R, Harmanli O. Voided Volume for Assessment of Bladder Emptying After Female Pelvic Floor Surgery: A Randomized Controlled Trial. Urogynecology 2022, 28: 811-818. PMID: 36409638, DOI: 10.1097/spv.0000000000001230.Peer-Reviewed Original ResearchConceptsUrogynecologic surgeryRF groupVoided volumeSV groupUrinary tract infection rateAssessment of bladderUrinary tract infectionML of salinePelvic floor surgerySpontaneous VTVoid trialBaseline characteristicsCatheter removalPrimary outcomePrior hysterectomyTract infectionsUrinary incontinenceControlled TrialsFemale pelvic floor surgeryPatient satisfactionUrogynecologic proceduresFailure rateSurgeryInfection rateGroup SV
2011
Cost-Effectiveness of Percutaneous Tibial Nerve Stimulation Versus Extended Release Tolterodine for Overactive Bladder
Chen HW, Bercik RS, Werner EF, Thung SF. Cost-Effectiveness of Percutaneous Tibial Nerve Stimulation Versus Extended Release Tolterodine for Overactive Bladder. Journal Of Urology 2011, 187: 178-184. PMID: 22100006, DOI: 10.1016/j.juro.2011.09.052.Peer-Reviewed Original ResearchConceptsPercutaneous tibial nerve stimulationTibial nerve stimulationQuality of lifeExtended release tolterodineIncremental cost-effectiveness ratioNerve stimulationTolterodine EROveractive bladderCost-effectiveness ratioSide effectsUrinary incontinencePercutaneous tibial nerve stimulation therapyTherapy side effectsSignificant side effectsCost-effectiveness modelMaintenance therapyImproved continencePrimary outcomeClinical circumstancesStimulation therapyMedical costsReduced qualityTherapy terminationBladderSocietal perspectiveOne-year objective and functional outcomes of a randomized clinical trial of vaginal mesh for prolapse
Sokol AI, Iglesia CB, Kudish BI, Gutman RE, Shveiky D, Bercik R, Sokol ER. One-year objective and functional outcomes of a randomized clinical trial of vaginal mesh for prolapse. American Journal Of Obstetrics And Gynecology 2011, 206: 86.e1-86.e9. PMID: 21974992, DOI: 10.1016/j.ajog.2011.08.003.Peer-Reviewed Original ResearchConceptsVaginal prolapse repairQuality of lifeReoperation rateMesh exposureProlapse repairSimilar recurrence ratesHigher reoperation rateRandomized clinical trialsProlapse stageEvaluable participantsPrimary outcomeSecondary outcomesBulge symptomsVaginal repairRecurrence rateFunctional outcomeSubjective improvementClinical trialsMesh repairVaginal meshTraditional repairMonthsOutcomesWomenProlapse
2009
Ischiorectal abscess and ischiorectal-vaginal fistula as delayed complications of posterior intravaginal slingplasty: a case report.
Chen HW, Guess MK, Connell KA, Bercik RS. Ischiorectal abscess and ischiorectal-vaginal fistula as delayed complications of posterior intravaginal slingplasty: a case report. The Journal Of Reproductive Medicine 2009, 54: 645-8. PMID: 20677486.Peer-Reviewed Original ResearchConceptsPosterior intravaginal slingplastyIntravaginal slingplastyIschiorectal abscessSling erosionPosterior intravaginal slingRight buttock painRight ischiorectal fossaVaginal fistula repairTotal vaginal hysterectomyPosterior vaginal prolapsePelvic organ prolapseLong-term safetyCopious vaginal dischargeMesh-augmented anterior repairMagnetic resonance imagingButtock painGradual symptomsSUSPEND trialMonth followupRight buttockVaginal hysterectomyAnterior repairApical prolapsePelvic abscessSurgical managementHOXA11 Promotes Fibroblast Proliferation and Regulates p53 in Uterosacral Ligaments
Connell KA, Guess MK, Chen HW, Lynch T, Bercik R, Taylor HS. HOXA11 Promotes Fibroblast Proliferation and Regulates p53 in Uterosacral Ligaments. Reproductive Sciences 2009, 16: 694-700. PMID: 19372592, PMCID: PMC3107841, DOI: 10.1177/1933719109334260.Peer-Reviewed Original ResearchConceptsCell proliferationExtracellular matrix proteinsTumor suppressor geneECM genesExpression of HOXA11Cell cycleMatrix proteinsSuppressor geneMurine fibroblastsRegulate p53Phenotypic abnormalitiesGenesHOXA11Rate of proliferationHOXA11 expressionExpressionP53ProliferationExpression of p53Fibroblast proliferationKey support structuresProteinHomeostasisDevelopment of POPBetter understandingDiminished vaginal HOXA13 expression in women with pelvic organ prolapse
Connell KA, Guess MK, Tate A, Andikyan V, Bercik R, Taylor HS. Diminished vaginal HOXA13 expression in women with pelvic organ prolapse. Menopause The Journal Of The North American Menopause Society 2009, 16: 529-533. PMID: 19423998, PMCID: PMC2704499, DOI: 10.1097/gme.0b013e31818fb0c2.Peer-Reviewed Original ResearchConceptsPelvic organ prolapsePremenopausal controlsPremenopausal womenOrgan prolapseHOXA13 expressionPOP groupExpression of HOXA13Real-time polymerase chain reactionExtracellular matrix metabolismEstrogen therapyPostmenopausal womenYounger patientsLeuprolide groupSmoking cessationLeuprolide acetatePolymerase chain reactionBiopsy specimensPreventive strategiesGenetic predispositionVaginal expressionProlapseMatrix metabolismWeight lossWomenVagina
2008
HOXA11 is critical for development and maintenance of uterosacral ligaments and deficient in pelvic prolapse
Connell KA, Guess MK, Chen H, Andikyan V, Bercik R, Taylor HS. HOXA11 is critical for development and maintenance of uterosacral ligaments and deficient in pelvic prolapse. Journal Of Clinical Investigation 2008, 118: 1050-1055. PMID: 18274672, PMCID: PMC2242622, DOI: 10.1172/jci34193.Peer-Reviewed Original Research
2007
Anterior intravaginal slingplasty tunneller device for stress incontinence and posterior intravaginal slingplasty for apical vault prolapse: a 2-year prospective multicenter study
Vardy MD, Brodman M, Olivera CK, Zhou HS, Flisser AJ, Bercik RS. Anterior intravaginal slingplasty tunneller device for stress incontinence and posterior intravaginal slingplasty for apical vault prolapse: a 2-year prospective multicenter study. American Journal Of Obstetrics And Gynecology 2007, 197: 104.e1-104.e8. PMID: 17618778, DOI: 10.1016/j.ajog.2007.03.056.Peer-Reviewed Original ResearchConceptsPosterior intravaginal slingplastyPelvic Floor Impact QuestionnaireCough stress testProspective multicenter studyIntravaginal slingplastyStress incontinenceMulticenter studyImpact QuestionnaireNegative cough stress testPelvic organ prolapse quantitationPelvic Floor Impact Questionnaire scoresVaginal mesh extrusionUrodynamic stress incontinenceRate of perforationStress testApical prolapseApical supportVault prolapseQuestionnaire scoresStress test resultsMesh extrusionPatientsMonthsEarly extrusionIncontinence