2011
One-year objective and functional outcomes of a randomized clinical trial of vaginal mesh for prolapse
Sokol AI, Iglesia CB, Kudish BI, Gutman RE, Shveiky D, Bercik R, Sokol ER. One-year objective and functional outcomes of a randomized clinical trial of vaginal mesh for prolapse. American Journal Of Obstetrics And Gynecology 2011, 206: 86.e1-86.e9. PMID: 21974992, DOI: 10.1016/j.ajog.2011.08.003.Peer-Reviewed Original ResearchConceptsVaginal prolapse repairQuality of lifeReoperation rateMesh exposureProlapse repairSimilar recurrence ratesHigher reoperation rateRandomized clinical trialsProlapse stageEvaluable participantsPrimary outcomeSecondary outcomesBulge symptomsVaginal repairRecurrence rateFunctional outcomeSubjective improvementClinical trialsMesh repairVaginal meshTraditional repairMonthsOutcomesWomenProlapse
2009
Diminished vaginal HOXA13 expression in women with pelvic organ prolapse
Connell KA, Guess MK, Tate A, Andikyan V, Bercik R, Taylor HS. Diminished vaginal HOXA13 expression in women with pelvic organ prolapse. Menopause The Journal Of The North American Menopause Society 2009, 16: 529-533. PMID: 19423998, PMCID: PMC2704499, DOI: 10.1097/gme.0b013e31818fb0c2.Peer-Reviewed Original ResearchConceptsPelvic organ prolapsePremenopausal controlsPremenopausal womenOrgan prolapseHOXA13 expressionPOP groupExpression of HOXA13Real-time polymerase chain reactionExtracellular matrix metabolismEstrogen therapyPostmenopausal womenYounger patientsLeuprolide groupSmoking cessationLeuprolide acetatePolymerase chain reactionBiopsy specimensPreventive strategiesGenetic predispositionVaginal expressionProlapseMatrix metabolismWeight lossWomenVagina