2020
Anger recall mental stress decreases 123I-metaiodobenzylguanidine (123I-MIBG) uptake and increases heterogeneity of cardiac sympathetic activity in the myocardium in patients with ischemic cardiomyopathy
Avendaño R, Hashemi-Zonouz T, Sandoval V, Liu C, Burg M, Sinusas AJ, Lampert R, Liu YH. Anger recall mental stress decreases 123I-metaiodobenzylguanidine (123I-MIBG) uptake and increases heterogeneity of cardiac sympathetic activity in the myocardium in patients with ischemic cardiomyopathy. Journal Of Nuclear Cardiology 2020, 29: 798-809. PMID: 33034036, DOI: 10.1007/s12350-020-02372-1.Peer-Reviewed Original ResearchConceptsSympathetic activityIschemic cardiomyopathyVentricular arrhythmiasICM patientsMental stressAge-matched healthy male controlsCardiac sympathetic activityHealthy control subjectsMyocardial sympathetic activityHealthy male controlsMental stress taskSPECT/CTMediastinal ratioControl subjectsHemodynamic responseAnger recallMyocardial perfusionNormal subjectsMale controlsPatientsPerfusionPsychological stressorsArrhythmiasStress taskDual-isotope imaging
2018
Combined Endocardial-Epicardial Versus Endocardial Catheter Ablation Alone for Ventricular Tachycardia in Structural Heart Disease A Systematic Review and Meta-Analysis
Romero J, Cerrud-Rodriguez R, Di Biase L, Diaz J, Alviz I, Grupposo V, Cerna L, Avendano R, Tedrow U, Natale A, Tung R, Kumar S. Combined Endocardial-Epicardial Versus Endocardial Catheter Ablation Alone for Ventricular Tachycardia in Structural Heart Disease A Systematic Review and Meta-Analysis. JACC Clinical Electrophysiology 2018, 5: 13-24. PMID: 30678778, DOI: 10.1016/j.jacep.2018.08.010.Peer-Reviewed Original ResearchConceptsArrhythmogenic right ventricular cardiomyopathyVentricular tachycardiaNonischemic cardiomyopathyIschemic cardiomyopathyProcedural complicationsVT recurrenceEndocardial ablationVT ablationLower riskSystematic reviewLimited single-center studyEndocardial catheter ablationSingle-center studyAcute procedural complicationsA Systematic ReviewRight ventricular cardiomyopathyCause mortalityCatheter ablationEmbase databasesVentricular cardiomyopathyAblation strategyNonsignificant trendSubsequent mortalityPatientsMeta-AnalysisPrevention of sudden cardiac death in ischaemic cardiomyopathy
Romero J, Natale A, Avendano R, Garcia M, Biase L. Prevention of sudden cardiac death in ischaemic cardiomyopathy. 2018, 2333-2337. DOI: 10.1093/med/9780198784906.003.0552.Peer-Reviewed Original ResearchLeft ventricular ejection fractionSudden cardiac deathAcute myocardial infarctionRisk stratificationMyocardial infarctionElectrophysiological studiesCardiac deathIschemic cardiomyopathyPrevention of SCDCardiac iodine-123 metaiodobenzylguanidineIodine-123 metaiodobenzylguanidineTransient myocardial stunningCardiovascular magnetic resonance imagingVentricular ejection fractionPrimary prevention strategiesMajor health problemChronic myocardial infarctionImplantable cardioverter defibrillatorMagnetic resonance imagingEjection fractionVentricular arrhythmiasLVEF assessmentPrimary preventionMyocardial stunningCurrent guidelines
2017
Clinical impact of implantable cardioverter-defibrillator in primary prevention of total mortality in non-ischaemic cardiomyopathy: results from a meta-analysis of prospective randomized clinical trials
Romero J, Díaz J, Grushko M, Quispe R, Briceno D, Avendano R, Golive A, Pina I, Natale A, Garcia M, Jorde U, Di Biase L. Clinical impact of implantable cardioverter-defibrillator in primary prevention of total mortality in non-ischaemic cardiomyopathy: results from a meta-analysis of prospective randomized clinical trials. EP Europace 2017, 20: f211-f216. PMID: 29161424, DOI: 10.1093/europace/eux324.Peer-Reviewed Original ResearchConceptsNon-ischemic cardiomyopathyImplantable cardioverter defibrillatorCause mortalityNICM patientsPrimary ProphylacTic Implantable Cardioverter DefibrillatorsRole of ICDUse of ICDsTotal mortalityProphylactic implantable cardioverter defibrillatorProspective randomized clinical trialsCardiac resynchronization therapy pacemakerCause mortality benefitProphylactic ICD placementMedical therapy groupRandomized clinical trialsRandom-effects modelSignificant reductionFixed-effects modelMean followMortality benefitICD groupIschemic cardiomyopathyMedical therapyICD placementTreatment arms