Genome wide instability scanning in chewing-tobacco associated oral cancer using inter simple sequence repeat PCR
Rai R, Kulkarni V, Saranath D. Genome wide instability scanning in chewing-tobacco associated oral cancer using inter simple sequence repeat PCR. Oral Oncology 2004, 40: 1033-1039. PMID: 15509495, DOI: 10.1016/j.oraloncology.2004.05.009.Peer-Reviewed Original ResearchConceptsOral cancerTumor tissueNormal tissuesOral cancer patientsTumor-adjacent normal tissuesOral cancer samplesAdjacent normal tissuesMultiple tumor tissuesCancer patientsNormal tissue DNATumor progressionCancer samplesGenomic instability indexCancerTissue DNAGenomic alterationsTumor heterogeneityGenomic instabilityTissueMolecular cloning, isolation and characterisation of ERK3 gene from chewing-tobacco induced oral squamous cell carcinoma
Rai R, Mahale A, Saranath D. Molecular cloning, isolation and characterisation of ERK3 gene from chewing-tobacco induced oral squamous cell carcinoma. Oral Oncology 2004, 40: 705-712. PMID: 15172640, DOI: 10.1016/j.oraloncology.2004.01.010.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceBlotting, NorthernBlotting, SouthernCarcinoma, Squamous CellCloning, MolecularDNA, ComplementaryDNA, NeoplasmGene ExpressionGene LibraryHumansMitogen-Activated Protein Kinase 6Mitogen-Activated Protein KinasesMolecular Sequence DataMouth NeoplasmsReverse Transcriptase Polymerase Chain ReactionTobacco, SmokelessConceptsOral cancer tissuesOral squamous cell carcinomaSquamous cell carcinomaPeripheral blood cellsNormal healthy individualsCancer tissuesExtracellular signal-regulated protein kinaseCell carcinomaOral cancerHealthy individualsNon-coding regionBlood cellsSerine/threonine kinaseSignal-regulated protein kinaseTobacco habitsC-Jun N-terminal kinaseFetal skeletal muscleMRNA transcript analysisNormal individualsN-terminal kinaseRegulation of mRNAPatient samplesRT-PCR analysisSkeletal muscleERK3 expression