Pathogen-specific leptospiral proteins in urine of patients with febrile illness aids in differential diagnosis of leptospirosis from dengue
Chaurasia R, Thresiamma K, Eapen C, Zachariah B, Paul R, Sritharan M. Pathogen-specific leptospiral proteins in urine of patients with febrile illness aids in differential diagnosis of leptospirosis from dengue. European Journal Of Clinical Microbiology & Infectious Diseases 2018, 37: 423-433. PMID: 29332210, DOI: 10.1007/s10096-018-3187-9.Peer-Reviewed Original ResearchConceptsMicroscopic agglutination testAnti-leptospiral antibodiesEnzyme-linked immunosorbent assayLeptospiral antigensDifferential diagnosisGroup I patientsUrine of patientsPUO patientsI patientsUrinary antigenClinical symptomsDengue patientsNon-invasive methodStudy groupPatientsHigh titresDengue feverAgglutination testUnknown originInfectious diseasesAntigenDiagnosisImmunosorbent assayUrine samplesSpecific antibodies