Ramesh Batra, MBBS, MA, FACS, FRCS
Associate Professor of Surgery (Transplant)Cards
About
Research
Publications
Featured Publications
Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning
Kucukkaya A, Zeevi T, Chai N, Raju R, Haider S, Elbanan M, Petukhova-Greenstein A, Lin M, Onofrey J, Nowak M, Cooper K, Thomas E, Santana J, Gebauer B, Mulligan D, Staib L, Batra R, Chapiro J. Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning. Scientific Reports 2023, 13: 7579. PMID: 37165035, PMCID: PMC10172370, DOI: 10.1038/s41598-023-34439-7.Peer-Reviewed Original ResearchThe Dead Donor Rule, Reversibility and Donor Wishes
Batra R, Latham S. The Dead Donor Rule, Reversibility and Donor Wishes. The American Journal Of Bioethics 2023, 23: 31-32. PMID: 36681919, DOI: 10.1080/15265161.2022.2159581.Peer-Reviewed Original ResearchPrediction of Death after Terminal Extubation, the Machine Learning Way
Huang J, Shung D, Burman T, Krishnaswamy S, Batra R. Prediction of Death after Terminal Extubation, the Machine Learning Way. Journal Of The American College Of Surgeons 2022, 235: s95-s96. DOI: 10.1097/01.xcs.0000896548.82546.55.Peer-Reviewed Original ResearchOutcomes of Simultaneous Liver‐Kidney Transplantation Using Kidneys of Deceased Donors With Acute Kidney Injury
Batra RK, Ariyamuthu VK, MacConmara MP, Gupta G, Gungor AB, Tanriover B. Outcomes of Simultaneous Liver‐Kidney Transplantation Using Kidneys of Deceased Donors With Acute Kidney Injury. Liver Transplantation 2022, 28: 983-997. PMID: 35006615, DOI: 10.1002/lt.26406.Peer-Reviewed Original ResearchConceptsSimultaneous liver-kidney transplantationDeath-censored graft failureAcute kidney injuryLiver-kidney transplantationDeceased donorsKidney injuryGraft failureSCr levelsMultivariable Cox proportional hazards modelsTerminal serum creatinine levelTransplantation Network registry dataCox proportional hazards modelShorter cold ischemia timeCause graft failureGood organ qualitySerum creatinine levelsCold ischemia timeInternational consensus guidelinesProportional hazards modelLiver transplantCreatinine levelsPrimary outcomeStudy cohortIschemia timeKidney diseaseThe use of nondirected donor organs in living donor liver transplantation: Perspectives and guidance
Fox AN, Liapakis A, Batra R, Bittermann T, Emamaullee J, Emre S, Genyk Y, Han H, Jackson W, Pomfret E, Raza M, Rodriguez‐Davalos M, Gold S, Samstein B, Shenoy A, Taner T, Roberts JP, Group T. The use of nondirected donor organs in living donor liver transplantation: Perspectives and guidance. Hepatology 2022, 75: 1579-1589. PMID: 34859474, DOI: 10.1002/hep.32260.Peer-Reviewed Original ResearchFrailty, an Imperfect ICU Rationing Criterion
Batra RK, Latham SR. Frailty, an Imperfect ICU Rationing Criterion. The American Journal Of Bioethics 2021, 21: 69-71. PMID: 34710005, DOI: 10.1080/15265161.2021.1980142.Peer-Reviewed Original ResearchNeural network predicts need for red blood cell transfusion for patients with acute gastrointestinal bleeding admitted to the intensive care unit
Shung D, Huang J, Castro E, Tay JK, Simonov M, Laine L, Batra R, Krishnaswamy S. Neural network predicts need for red blood cell transfusion for patients with acute gastrointestinal bleeding admitted to the intensive care unit. Scientific Reports 2021, 11: 8827. PMID: 33893364, PMCID: PMC8065139, DOI: 10.1038/s41598-021-88226-3.Peer-Reviewed Original ResearchConceptsAcute gastrointestinal bleedingRed blood cell transfusionBlood cell transfusionGastrointestinal bleedingHigh-risk patientsCell transfusionRed blood cellsPatient cohortIntensive Care III (MIMIC-III) critical care databaseIntensive care unit staySevere acute gastrointestinal bleedingPacked red blood cellsBlood cellsCommon gastrointestinal causesLaboratory test featuresTime-updated dataIntensive care unitValidation patient cohortCritical care databaseLarge urban hospitalMedical Information MartInternal validation setGastrointestinal causesUnit stayCare unitMachine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study.
Iseke S, Zeevi T, Kucukkaya AS, Raju R, Gross M, Haider SP, Petukhova-Greenstein A, Kuhn TN, Lin M, Nowak M, Cooper K, Thomas E, Weber MA, Madoff DC, Staib L, Batra R, Chapiro J. Machine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study. American Journal Of Roentgenology 2022, 220: 245-255. PMID: 35975886, PMCID: PMC10015590, DOI: 10.2214/ajr.22.28077.Peer-Reviewed Original ResearchConceptsEarly-stage hepatocellular carcinomaLiver transplantHepatocellular carcinomaImaging featuresPosttreatment recurrenceOrgan allocationMean AUCLiver transplant eligibilityPretreatment clinical characteristicsPretreatment MRI examinationsKaplan-Meier analysisKaplan-Meier curvesClinical characteristicsImaging surveillanceTherapy allocationTransplant eligibilityUnderwent treatmentClinical parametersRetrospective studyUnpredictable complicationMRI dataConcept studyPoor survivalClinical impactPretreatment MRIClinical and Ethical Framework for Liver Retransplantation Using Living Donor Grafts: A Western Perspective
Batra RK, Mulligan DC. Clinical and Ethical Framework for Liver Retransplantation Using Living Donor Grafts: A Western Perspective. Liver Transplantation 2022, 28: 760-762. PMID: 34931433, DOI: 10.1002/lt.26395.Peer-Reviewed Original ResearchInactive status is an independent predictor of liver transplant waitlist mortality and is associated with a transplant centers median meld at transplant
Merola J, Gan G, Stewart D, Noreen S, Mulligan D, Batra R, Haakinson D, Deng Y, Kulkarni S. Inactive status is an independent predictor of liver transplant waitlist mortality and is associated with a transplant centers median meld at transplant. PLOS ONE 2021, 16: e0260000. PMID: 34793524, PMCID: PMC8601542, DOI: 10.1371/journal.pone.0260000.Peer-Reviewed Original ResearchConceptsDonor service areasWaitlist mortalityTransplant centersMedian MELDHigh mortalityStatus changesLiver transplant waitlist mortalityDeceased donor transplantsInactive statusTransplant probabilityInactive patientsMELD scoreDonor transplantsHazard ratioIndependent predictorsTransplant ratesCare coordinationMortalityPatientsTransplantLevel cohortsTertileSignificant differencesCohortMELD
Clinical Trials
Current Trials
HOPE in Action Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients
HIC ID2000025220RoleSub InvestigatorPrimary Completion Date06/30/2024Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
Clinical Care
Overview
Ramesh Batra, MD, is an adult and pediatric abdominal transplant surgeon who performs kidney, liver and pancreas transplants. He also performs complex hepatobiliary procedures for people with liver tumors and biliary tract disorders, as well as general surgery procedures for those with liver cirrhosis and kidney failure.
Dr. Batra chose this field, in part, because he had an early interest in engineering and thought transplant surgery to be just as complex and challenging. “We put the patient at the center of our care, and the entire transplant team, which includes transplant surgeons, nephrologists, hepatologists, dietitians, pharmacists, social workers and coordinators, working together for the betterment of that patient.”
Transplantation surgeries have undergone significant refinements in the last six decades or so, says Dr. Batra. “Both liver transplant and kidney transplant surgeries can now be done in a third of the time it used to take in the initial years,” he says. Anti-rejection medications that are less toxic and more tolerable have also contributed to longer lasting transplants, including much more sophisticated post-transplant care
However, the shortage of organs to transplant is still a critical problem, with almost 20 patients dying on the waiting list every day, says Dr. Batra, who is an assistant professor of surgery (transplant and immunology) at Yale School of Medicine. “There is much more need than there is availability, and we’ve got to bridge this gap,” he says. He is interested in promoting living organ donation, and he focuses his research on the careful use of extended spectrum organs—finding ways to maximize organs that may seem less than perfect to get the best benefit for a suitable recipient.
Many patients remain in Dr. Batra’s thoughts. One was a sick infant who needed a liver transplant. “An altruistic living donor came forward—somebody who wanted to donate a piece of her liver out of the goodness of her heart, and we were able to successfully complete the donation and transplantation operation. It's powerful moments like these where you feel you're doing the right thing in supporting the mission of saving the most lives,” Dr. Batra says.
Clinical Specialties
Fact Sheets
Liver Transplant
Learn More on Yale MedicineKidney Transplant
Learn More on Yale MedicineGastroenteritis
Learn More on Yale MedicineAnesthesia for Organ Transplant
Learn More on Yale Medicine
Board Certifications
Surgery General
- Certification Organization
- Royal College of Surgeons of Edinburgh
- Original Certification Date
- 2012