2023
Pre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers
Hennein R, Lowe S, Feingold J, Feder A, Peccoralo L, Ripp J, Mazure C, Pietrzak R. Pre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers. Journal Of Psychiatric Research 2023, 162: 88-94. PMID: 37105023, DOI: 10.1016/j.jpsychires.2023.04.009.Peer-Reviewed Original ResearchConceptsMajor depressive disorderPosttraumatic stress disorderProspective cohort studyHealthcare providersCohort studyLarge tertiary care hospitalPsychological sequelaeSymptoms of MDDMental health risk factorsTertiary care hospitalProbable major depressive disorderWomen's healthcare providersHealth risk factorsFrontline healthcare providersCare hospitalRisk factorsDepressive disorderGender differencesStress disorderAnxiety disordersWomenSequelaeCOVID-19DisordersCOVID-19 pandemic
2021
Are Women Less Psychologically Resilient Than Men? Background Stressors Underlying Gender Differences in Reports of Stress-Related Psychological Sequelae.
Lowe SR, Hennein R, Feingold JH, Peccoralo LA, Ripp JA, Mazure CM, Pietrzak RH. Are Women Less Psychologically Resilient Than Men? Background Stressors Underlying Gender Differences in Reports of Stress-Related Psychological Sequelae. The Journal Of Clinical Psychiatry 2021, 83 PMID: 34936244, DOI: 10.4088/jcp.21br14098.Peer-Reviewed Original Research“They Wanted to Talk to a ‘Real Doctor’”: Predictors, Perpetrators, and Experiences of Racial and Ethnic Discrimination Among Healthcare Workers
Hennein R, Tineo P, Bonumwezi J, Gorman H, Nguemeni Tiako MJ, Lowe SR. “They Wanted to Talk to a ‘Real Doctor’”: Predictors, Perpetrators, and Experiences of Racial and Ethnic Discrimination Among Healthcare Workers. Journal Of General Internal Medicine 2021, 37: 1475-1483. PMID: 34561823, PMCID: PMC8475391, DOI: 10.1007/s11606-021-07143-3.Peer-Reviewed Original ResearchImplementation of a volunteer contact tracing program for COVID-19 in the United States: A qualitative focus group study
Shelby T, Hennein R, Schenck C, Clark K, Meyer AJ, Goodwin J, Weeks B, Bond M, Niccolai L, Davis JL, Grau LE. Implementation of a volunteer contact tracing program for COVID-19 in the United States: A qualitative focus group study. PLOS ONE 2021, 16: e0251033. PMID: 33951107, PMCID: PMC8099418, DOI: 10.1371/journal.pone.0251033.Peer-Reviewed Original ResearchSocio-ecological predictors of mental health outcomes among healthcare workers during the COVID-19 pandemic in the United States
Hennein R, Mew EJ, Lowe SR. Socio-ecological predictors of mental health outcomes among healthcare workers during the COVID-19 pandemic in the United States. PLOS ONE 2021, 16: e0246602. PMID: 33544761, PMCID: PMC7864435, DOI: 10.1371/journal.pone.0246602.Peer-Reviewed Original ResearchConceptsProbable major depressionProbable posttraumatic stress disorderAlcohol use disorderPosttraumatic stress disorderMental health outcomesMajor depressionHealthcare workersHealth outcomesPrimary care Post Traumatic Stress DisorderPersonal Health Questionnaire-9Multivariable logistic regression modelStress disorderCOVID-19 pandemicGeneralized Anxiety Disorder-7Online cross-sectional studyMultivariable adjusted modelsAdverse mental health outcomesAnxiety Disorder-7Cross-sectional studyPost-traumatic stress disorderLogistic regression modelsQuestionnaire-9Mean ageAdjusted associationsSocio-ecological levels
2020
A hybrid inductive-abductive analysis of health workers’ experiences and wellbeing during the COVID-19 pandemic in the United States
Hennein R, Lowe S. A hybrid inductive-abductive analysis of health workers’ experiences and wellbeing during the COVID-19 pandemic in the United States. PLOS ONE 2020, 15: e0240646. PMID: 33104711, PMCID: PMC7588050, DOI: 10.1371/journal.pone.0240646.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholismAnxiety DisordersBetacoronavirusCommunity-Institutional RelationsCoronavirus InfectionsCOVID-19Cross-Sectional StudiesDepressive DisorderFemaleHealth BehaviorHealth PersonnelHealth PolicyHumansInterpersonal RelationsMaleModels, TheoreticalOccupational StressPandemicsPatient Health QuestionnairePneumonia, ViralSARS-CoV-2Social Determinants of HealthStress Disorders, Post-TraumaticUnited StatesConceptsHealth workers' experiencesProbable major depressionHealth workersAlcohol use disorderPost-traumatic stress disorderStress disorderMajor depressionUse disordersPatient Health Questionnaire-9Probable alcohol use disorderAlcohol Use Disorders Identification Test-ConciseProbable post-traumatic stress disorderGeneralized Anxiety Disorder-7Anxiety disordersAdverse mental health outcomesSelf-care behaviorsMental health morbidityAnxiety Disorder-7Probable generalized anxiety disorderMental health conditionsCOVID-19COVID-19 pandemicGeneralized anxiety disorderMental health outcomesInterpersonal level themes
2019
Increased Diet Quality is Associated with Long‐Term Reduction of Abdominal and Pericardial Fat
Hennein R, Liu C, McKeown NM, Hoffmann U, Long MT, Levy D, Ma J. Increased Diet Quality is Associated with Long‐Term Reduction of Abdominal and Pericardial Fat. Obesity 2019, 27: 670-677. PMID: 30825267, PMCID: PMC6430652, DOI: 10.1002/oby.22427.Peer-Reviewed Original ResearchConceptsMediterranean-style diet scoreLess fat accumulationGenetic risk scoreFat accumulationDiet qualityAdipose tissueAbdominal subcutaneous adipose tissueEctopic fat depotsEctopic fat accumulationGenetic riskFramingham Heart Study participantsVisceral adipose tissuePericardial adipose tissueSubcutaneous adipose tissueDiet scorePericardial fatLong-term reductionRisk scoreFat depotsAdiposity profilesStudy participantsSD improvementFavorable changesLongitudinal associationsLongitudinal improvementA Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease
Ma J, Nano J, Ding J, Zheng Y, Hennein R, Liu C, Speliotes EK, Huan T, Song C, Mendelson MM, Joehanes R, Long MT, Liang L, Smith JA, Reynolds LM, Ghanbari M, Muka T, van Meurs JBJ, Alferink LJM, Franco OH, Dehghan A, Ratliff S, Zhao W, Bielak L, Kardia SLR, Peyser PA, Ning H, VanWagner LB, Lloyd-Jones DM, Carr JJ, Greenland P, Lichtenstein AH, Hu FB, Liu Y, Hou L, Murad S, Levy D. A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease. Diabetes 2019, 68: 1073-1083. PMID: 30936141, PMCID: PMC6477898, DOI: 10.2337/db18-1193.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseFatty liver diseaseHepatic fatDNA methylation signaturesLiver diseasePopulation-based cohort studyMethylation signaturesNew-onset T2DType 2 diabetesHepatic fat accumulationMendelian randomization analysisCohort studyPotential causal pathwaysRisk factorsFat accumulationAfrican ancestry participantsEuropean ancestry participantsAttractive biomarkerCytosine-guanine dinucleotidesAssociation of hypomethylationWhole bloodHispanic ancestryRandomization analysisSame CpGsCausal pathways
2018
Barriers to medication adherence and links to cardiovascular disease risk factor control: the Framingham Heart Study
Hennein R, Hwang S, Au R, Levy D, Muntner P, Fox CS, Ma J. Barriers to medication adherence and links to cardiovascular disease risk factor control: the Framingham Heart Study. Internal Medicine Journal 2018, 48: 414-421. PMID: 29193523, PMCID: PMC5889324, DOI: 10.1111/imj.13687.Peer-Reviewed Original ResearchConceptsCVD risk factorsMini-Mental State ExaminationMedication adherenceLow adherenceRisk factorsFramingham Heart StudyCardiovascular diseaseDepressive symptomsHeart StudyCardiovascular disease risk factor controlHigher mean diastolic blood pressureMean low-density lipoprotein cholesterolFour-item Morisky Medication Adherence ScaleMean diastolic blood pressureMedian age 70 yearsLow-density lipoprotein cholesterolMorisky Medication Adherence ScaleFive-unit increaseRisk factor controlLipid-lowering medicationsDiastolic blood pressureMedication Adherence ScaleAge 70 yearsLow medication adherenceCES-D scoresImproved Diet Quality Associates With Reduction in Liver Fat, Particularly in Individuals With High Genetic Risk Scores for Nonalcoholic Fatty Liver Disease
Ma J, Hennein R, Liu C, Long MT, Hoffmann U, Jacques PF, Lichtenstein AH, Hu FB, Levy D. Improved Diet Quality Associates With Reduction in Liver Fat, Particularly in Individuals With High Genetic Risk Scores for Nonalcoholic Fatty Liver Disease. Gastroenterology 2018, 155: 107-117. PMID: 29604292, PMCID: PMC6035111, DOI: 10.1053/j.gastro.2018.03.038.Peer-Reviewed Original ResearchConceptsMediterranean-style diet scoreNonalcoholic fatty liver diseaseAlternative Healthy Eating IndexGenetic risk scoreHigh genetic risk scoreDiet quality changesIncident fatty liverFatty liver diseaseLiver fat accumulationFatty liverDiet scoreLiver fatRisk scoreFramingham Heart StudyAHEI scoreLiver diseaseFat accumulationHeart StudyHarvard Food Frequency QuestionnaireDiet qualityFood frequency questionnaireThird Generation cohortsHealthy Eating IndexAssociation of changesStandard deviation increase