2014
Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin
Rossier J, Bernard A, Cabungcal J, Perrenoud Q, Savoye A, Gallopin T, Hawrylycz M, Cuénod M, Do K, Urban A, Lein E. Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin. Molecular Psychiatry 2014, 20: 154-161. PMID: 25510509, PMCID: PMC4356748, DOI: 10.1038/mp.2014.162.Peer-Reviewed Original ResearchConceptsPerineuronal netsSomatosensory cerebral cortexWisteria floribunda agglutininCerebral cortexParvalbumin interneuronsCortical interneuronsInterneuron markersAmyloid β-peptidePatch clampAllen Mouse Brain AtlasInterneuronsPattern of expressionSpecific markersMouse Brain AtlasPvalbAllen AtlasADAMTS15NeprilysinBrain atlasMultiplex PCRΒ-peptideMarkers
2009
Degenerative abnormalities in transgenic neocortical neuropeptide Y interneurons expressing tau‐green fluorescent protein
Rancillac A, Lainé J, Perrenoud Q, Geoffroy H, Ferezou I, Vitalis T, Rossier J. Degenerative abnormalities in transgenic neocortical neuropeptide Y interneurons expressing tau‐green fluorescent protein. Journal Of Neuroscience Research 2009, 88: 487-499. PMID: 19830842, DOI: 10.1002/jnr.22234.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsDendritesFluorescent Antibody TechniqueIn Vitro TechniquesInterneuronsLuminescent ProteinsLysineMaleMiceMice, Inbred C57BLMice, TransgenicMicroscopy, ImmunoelectronNeurodegenerative DiseasesNeuropeptide YPatch-Clamp TechniquesReverse Transcriptase Polymerase Chain ReactionSomatosensory CortexTau ProteinsConceptsLysosomal-associated membrane protein 1Bacterial artificial chromosomeGreen fluorescent proteinFluorescent proteinGene of interestElectrophysiological intrinsic propertiesTranscriptional controlTau-green fluorescent proteinArtificial chromosomesGenomic sequencesMembrane protein 1BAC transgenic miceReporter geneReporter constructsMorphological defectsLysosomal vacuolesCell typesProtein tauProtein 1Electrophysiological defectsRestricted spatial distributionElectron microscopic analysisGenesProteinTransgenic mice