2022
DeepLensNet: Deep Learning Automated Diagnosis and Quantitative Classification of Cataract Type and Severity
Keenan T, Chen Q, Agrón E, Tham Y, Goh J, Lei X, Ng Y, Liu Y, Xu X, Cheng C, Bikbov M, Jonas J, Bhandari S, Broadhead G, Colyer M, Corsini J, Cousineau-Krieger C, Gensheimer W, Grasic D, Lamba T, Magone M, Maiberger M, Oshinsky A, Purt B, Shin S, Thavikulwat A, Lu Z, Chew E, Group A, Ajilore P, Akman A, Azar N, Azar W, Chan B, Cox V, Dave A, Dhanjal R, Donovan M, Farrell M, Finkel F, Goblirsch T, Ha W, Hill C, Kumar A, Kent K, Lee A, Patel P, Peprah D, Piliponis E, Selzer E, Swaby B, Tenney S, Zeleny A. DeepLensNet: Deep Learning Automated Diagnosis and Quantitative Classification of Cataract Type and Severity. Ophthalmology 2022, 129: 571-584. PMID: 34990643, PMCID: PMC9038670, DOI: 10.1016/j.ophtha.2021.12.017.Peer-Reviewed Original ResearchConceptsAge-related cataractSingapore Malay Eye StudyAnterior segment photographsCortical lens opacitiesPosterior subcapsular cataractCommon typeSlit-lamp photographsLeast common typeMedical studentsEye StudyNuclear sclerosisSubcapsular cataractLens opacitiesCataract typesRetroillumination photographsCataract assessmentOphthalmologistsCataract severityCataractExternal validationDiagnosisSeveritySclerosisStudy dataset
2019
A Deep Learning Approach for Automated Detection of Geographic Atrophy from Color Fundus Photographs
Keenan T, Dharssi S, Peng Y, Chen Q, Agrón E, Wong W, Lu Z, Chew E. A Deep Learning Approach for Automated Detection of Geographic Atrophy from Color Fundus Photographs. Ophthalmology 2019, 126: 1533-1540. PMID: 31358385, PMCID: PMC6810830, DOI: 10.1016/j.ophtha.2019.06.005.Peer-Reviewed Original Research
2018
DeepSeeNet: A Deep Learning Model for Automated Classification of Patient-based Age-related Macular Degeneration Severity from Color Fundus Photographs
Peng Y, Dharssi S, Chen Q, Keenan T, Agrón E, Wong W, Chew E, Lu Z. DeepSeeNet: A Deep Learning Model for Automated Classification of Patient-based Age-related Macular Degeneration Severity from Color Fundus Photographs. Ophthalmology 2018, 126: 565-575. PMID: 30471319, PMCID: PMC6435402, DOI: 10.1016/j.ophtha.2018.11.015.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArea Under CurveDeep LearningDiagnosis, Computer-AssistedDiagnostic Techniques, OphthalmologicalDisease ProgressionFemaleGeographic AtrophyHumansMaleMiddle AgedModels, TheoreticalPhotographyProspective StudiesReproducibility of ResultsRetinal DrusenRisk FactorsSensitivity and SpecificitySeverity of Illness IndexConceptsLate age-related macular degenerationAge-related macular degenerationColor fundus photographsSeverity ScaleRetinal specialistsSeverity scoreDeep learning modelsLarge drusenFundus photographsPigmentary abnormalitiesAge-related macular degeneration (AMD) severityPatient-based scoring systemsAMD risk factorsRisk of progressionLearning modelEye Disease StudyDeep learning systemGold-standard labelsRisk factorsMacular degenerationIndividual patientsGrading processPatient-based classificationPatientsScoring system