2015
Incidence and predictors of post-ERCP pancreatitis in patients with suspected sphincter of Oddi dysfunction undergoing biliary or dual sphincterotomy: results from the EPISOD prospective multicenter randomized sham-controlled study
Yaghoobi M, Pauls Q, Durkalski V, Romagnuolo J, Fogel EL, Tarnasky PR, Aliperti G, Freeman ML, Kozarek RA, Jamidar PA, Wilcox CM, Elta GH, Hawes RH, Wood-Williams A, Cotton PB. Incidence and predictors of post-ERCP pancreatitis in patients with suspected sphincter of Oddi dysfunction undergoing biliary or dual sphincterotomy: results from the EPISOD prospective multicenter randomized sham-controlled study. Endoscopy 2015, 47: 884-890. PMID: 26165739, DOI: 10.1055/s-0034-1392418.Peer-Reviewed Original ResearchMeSH KeywordsAdultCholangiopancreatography, Endoscopic RetrogradeCommon Bile Duct DiseasesFemaleFollow-Up StudiesHumansIncidenceMaleManometryMiddle AgedPancreatitisPostoperative ComplicationsPressurePrognosisProspective StudiesSphincter of OddiSphincter of Oddi DysfunctionSphincterotomy, EndoscopicStentsUnited StatesYoung AdultConceptsPost-ERCP pancreatitisEndoscopic retrograde cholangiopancreatographyDual sphincterotomySedation typeOddi dysfunctionDevelopment of PEPRisk of PEPLife-threatening adverse eventsPancreatic sphincter pressuresPost-cholecystectomy patientsResults of sphincterSOD type IIIProphylactic pancreatic stentsSham-controlled studyEvaluating PredictorsPharmacological prophylaxisERCP pancreatitisProspective multicenterOddi manometryPancreatic stentingSphincter pressureAdverse eventsSham armBiliary sphincterotomyAcute pancreatitis
2014
Effect of Endoscopic Sphincterotomy for Suspected Sphincter of Oddi Dysfunction on Pain-Related Disability Following Cholecystectomy: The EPISOD Randomized Clinical Trial
Cotton PB, Durkalski V, Romagnuolo J, Pauls Q, Fogel E, Tarnasky P, Aliperti G, Freeman M, Kozarek R, Jamidar P, Wilcox M, Serrano J, Brawman-Mintzer O, Elta G, Mauldin P, Thornhill A, Hawes R, Wood-Williams A, Orrell K, Drossman D, Robuck P. Effect of Endoscopic Sphincterotomy for Suspected Sphincter of Oddi Dysfunction on Pain-Related Disability Following Cholecystectomy: The EPISOD Randomized Clinical Trial. JAMA 2014, 311: 2101-2109. PMID: 24867013, PMCID: PMC4428324, DOI: 10.1001/jama.2014.5220.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographySuccessful treatmentDual sphincterotomyAbdominal painOddi dysfunctionEndoscopic sphincterotomyBiliary sphincterotomyObservational study groupPancreatic sphincter hypertensionPancreatic sphincter pressuresReferral medical centerDays of disabilitySuccess of treatmentERCP interventionPancreatic sphincterotomyFinal followPain reliefManometry findingsSphincter pressureSphincterotomy groupManometry resultsNarcotic useRetrograde cholangiopancreatographySham groupClinical trials