2024
Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis
Ram C, Yousef S, Ma W, Vallabhajosyula I, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Williams M, Geirsson A, Vallabhajosyula P. Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis. Scientific Reports 2024, 14: 4952. PMID: 38418864, PMCID: PMC10902341, DOI: 10.1038/s41598-024-52660-w.Peer-Reviewed Original ResearchConceptsAortic valve replacementSevere aortic stenosisAfrican American raceArea Deprivation IndexAortic stenosisSevere ASArea deprivation index rankAortic valve replacement ratesAmerican raceAortic valve interventionPresentation of sepsisDiagnosis of ASADI groupValve replacementValve interventionDeprived neighbourhoodsAV interventionDisadvantaged neighborhoodsPatientsFemale genderDeprivation indexHigh-ADI groupLow-ADI groupStenosisRace
2018
Management of Patients With Coronary Artery Malperfusion Secondary to Type A Aortic Dissection
Kreibich M, Bavaria JE, Branchetti E, Brown CR, Chen Z, Khurshan F, Siki M, Vallabhajosyula P, Szeto WY, Desai ND. Management of Patients With Coronary Artery Malperfusion Secondary to Type A Aortic Dissection. The Annals Of Thoracic Surgery 2018, 107: 1174-1180. PMID: 30444990, DOI: 10.1016/j.athoracsur.2018.09.065.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCohort StudiesCoronary Artery BypassCoronary Artery DiseaseCoronary CirculationFemaleGermanyHeart Arrest, InducedHospital MortalityHospitals, UniversityHumansKaplan-Meier EstimateLength of StayMaleMiddle AgedPostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentStatistics, NonparametricSurvival AnalysisTreatment OutcomeConceptsCoronary artery malperfusionType B patientsType C patientsAntegrade cardioplegiaC patientsB patientsAortic dissectionCoronary ostiumDissection flapCA diseaseA Aortic DissectionType C lesionsManagement of patientsType B lesionsLong-term survivalCA bypassBypass GraftingPerioperative mortalityC lesionsComplete avulsionB lesionsLandmark analysisMalperfusionSuture repairPatientsTricuspid valve endocarditis in the era of the opioid epidemic
Wallen TJ, Szeto W, Williams M, Atluri P, Arnaoutakis G, Fults M, Sultan I, Desai N, Acker M, Vallabhajosyula P. Tricuspid valve endocarditis in the era of the opioid epidemic. Journal Of Cardiac Surgery 2018, 33: 260-264. PMID: 29663522, DOI: 10.1111/jocs.13600.Peer-Reviewed Original ResearchConceptsTricuspid valve endocarditisOpioid epidemicTricuspid endocarditisValve endocarditisRight heart endocarditisThirty-day mortalityTricuspid valve replacementCommon causative agentIndex hospitalizationRenal failureValve replacementSurgical volumeInstitutional experienceCommon isolatesExclusion criteriaEndocarditisAverage agePatientsStudy periodCausative agentStaphylococcus aureusEpidemicFivefold increaseReoperationHospitalization
2017
Fate of remnant sinuses of Valsalva in patients with bicuspid and trileaflet valves undergoing aortic valve, ascending aorta, and aortic arch replacement
Milewski RK, Habertheuer A, Bavaria JE, Siki M, Szeto WY, Krause E, Korutla V, Desai ND, Vallabhajosyula P. Fate of remnant sinuses of Valsalva in patients with bicuspid and trileaflet valves undergoing aortic valve, ascending aorta, and aortic arch replacement. Journal Of Thoracic And Cardiovascular Surgery 2017, 154: 421-432. PMID: 28599977, DOI: 10.1016/j.jtcvs.2017.03.150.Peer-Reviewed Original ResearchConceptsAortic valve replacementBicuspid aortic valveAorta replacementTricuspid aortic valveValve replacementAortic valveValsalva dimensionsPreoperative sinusSinus segmentValvular morphologyValvular pathologyElective aortic valve replacementMultivariable Cox regression modelsAortic arch replacementKaplan-Meier analysisAortic valve morphologyCox regression modelAortic valvulopathyArch replacementSurgical managementAortic aneurysmAortic rootLongitudinal sinusValsalva groupPatients
2016
Valve Selection in End-Stage Renal Disease: Should It Always Be Biological?
Williams ML, Bavaria JE, Acker MA, Desai ND, Vallabhajosyula P, Hargrove WC, Atluri P, Szeto WY. Valve Selection in End-Stage Renal Disease: Should It Always Be Biological? The Annals Of Thoracic Surgery 2016, 102: 1531-1535. PMID: 27544289, DOI: 10.1016/j.athoracsur.2016.04.092.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAnticoagulantsAortic ValveBioprosthesisCalcinosisContraindicationsEndocarditisHeart Valve DiseasesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansKaplan-Meier EstimateKidney Failure, ChronicMiddle AgedMitral ValvePostoperative ComplicationsProportional Hazards ModelsProsthesis-Related InfectionsRenal DialysisRetrospective StudiesThrombophiliaConceptsEnd-stage renal diseaseValve replacementProportional hazards modelESRD patientsMechanical valvesRenal diseaseHazards modelImproved long-term survivalCox proportional hazards modelAortic valve replacementMechanical valve replacementMitral valve replacementKaplan-Meier methodLong-term survivalValve selectionESRD populationPatient ageUnadjusted survivalImproved survivalPatient populationPatientsSurvivalDiseaseMinimal differencesYearsNew Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement.
Rene AG, Jagasia D, Wickramasinghe SR, Desai N, Szeto W, Vallabhajosyula P, Li RH, Silvestry FE, Giri J, Jha S, Herrmann HC, Anwaruddin S. New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement. Journal Of Invasive Cardiology 2016, 28: e59-65. PMID: 27342207.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic ValveAortic Valve StenosisEchocardiographyFemaleHeart Septal Defects, VentricularHumansMaleOutcome and Process Assessment, Health CarePostoperative ComplicationsQuality of LifeReoperationRisk AssessmentRisk FactorsSeverity of Illness IndexTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementLeft ventricular outflow tract calcificationSevere symptomatic aortic stenosisVentricular outflow tract calcificationSymptomatic aortic stenosisAortic valve replacementVentricular septal defectNew ventricular septal defectQuality of lifeInoperable patientsInfrequent complicationParavalvular regurgitationValve replacementAortic stenosisVascular injurySeptal defectPatientsComplicationsStudied populationRegurgitationStenosisInjuryStrokeCalcification
2015
Mechanical Circulatory Support as a Bridge to Definitive Surgical Repair After Post‐Myocardial Infarct Ventricular Septal Defect
Hobbs R, Korutla V, Suzuki Y, Acker M, Vallabhajosyula P. Mechanical Circulatory Support as a Bridge to Definitive Surgical Repair After Post‐Myocardial Infarct Ventricular Septal Defect. Journal Of Cardiac Surgery 2015, 30: 535-540. PMID: 25940559, DOI: 10.1111/jocs.12561.Peer-Reviewed Original ResearchConceptsVentricular septal defectMechanical circulatory supportSurgical repairCirculatory supportMyocardial infarctionSeptal defectPost-MI ventricular septal defectExtracorporeal membrane oxygenation bridgeDefinitive surgical repairEmergent cardiac surgeryMultisystem organ failureEmergency surgeryCardiac surgeryMedical stabilizationOrgan failureSerious complicationsMortality ratePatientsSurgeryRepairComplicationsInfarction
2014
Long-term results of aggressive hemiarch replacement in 534 patients with type A aortic dissection
Rylski B, Milewski RK, Bavaria JE, Vallabhajosyula P, Moser W, Szeto WY, Desai ND. Long-term results of aggressive hemiarch replacement in 534 patients with type A aortic dissection. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 2981-2985. PMID: 25112930, DOI: 10.1016/j.jtcvs.2014.05.093.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAged, 80 and overAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationFemaleHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPostoperative ComplicationsReoperationRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsDeBakey type IDistal aortic reinterventionHemiarch replacementAcute typeAortic reinterventionAortic dissectionDeBakey type I dissectionAdverse aortic eventsType I dissectionAortic arch aneurysmLong-term resultsType IAortic wall tissueDistal reinterventionHospital mortalityAortic eventsReoperation rateTotal archArch aneurysmIndependent predictorsReinterventionStudy populationMarfan syndromePatientsLower mortalityLong-Term Results of Neomedia Sinus Valsalva Repair in 489 Patients With Type A Aortic Dissection
Rylski B, Bavaria JE, Milewski RK, Vallabhajosyula P, Moser W, Kremens E, Pochettino A, Szeto WY, Desai ND. Long-Term Results of Neomedia Sinus Valsalva Repair in 489 Patients With Type A Aortic Dissection. The Annals Of Thoracic Surgery 2014, 98: 582-589. PMID: 24928674, DOI: 10.1016/j.athoracsur.2014.04.050.Peer-Reviewed Original ResearchModeling of predissection aortic size in acute type A dissection: More than 90% fail to meet the guidelines for elective ascending replacement
Rylski B, Branchetti E, Bavaria JE, Vallabhajosyula P, Szeto WY, Milewski RK, Desai ND. Modeling of predissection aortic size in acute type A dissection: More than 90% fail to meet the guidelines for elective ascending replacement. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 944-948.e1. PMID: 24998700, DOI: 10.1016/j.jtcvs.2014.05.050.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAortic AneurysmAortic DissectionAortographyBlood Vessel Prosthesis ImplantationEchocardiography, TransesophagealElective Surgical ProceduresFemaleGermanyGuideline AdherenceHumansIncidenceMaleMiddle AgedPatient SelectionPractice Guidelines as TopicPredictive Value of TestsRetrospective StudiesRisk FactorsTomography, X-Ray ComputedConceptsDissection onsetAcute typeAortic dissectionAorta diameterAortic diameterAscending aortaPreoperative computed tomography angiogramsComputed tomography angiogramAortic dissection onsetAcute dissectionAortic replacementAortic dilatationAortic sizeTomography angiogramBiochemical predictorsCurrent guidelinesPatientsDiameter increase ratePredissectionDissectionAortaMarfanOnsetWomenAdditional research