2024
Harnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer
Lindsay M, de Oliveira S, Sciacca K, Lindvall C, Ananth P. Harnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer. JCO Clinical Cancer Informatics 2024, 8: e2400134. PMID: 39265122, PMCID: PMC11407740, DOI: 10.1200/cci.24.00134.Peer-Reviewed Original ResearchConceptsEnd-of-life carePalliative care consultationGoals of careLocation of deathProportion of decedentsDocumented discussionCare consultationEvidence-based quality measuresMeasure quality of careGold standard manual chart reviewQuality measuresQuality of careEnd of lifeContent of clinical notesLife-sustaining treatmentEnd-of-lifeManual chart reviewCancer decedentsEfficient quality measureCohort of childrenAssess qualityMulti-center researchQuality improvementMeasure qualityCare
2021
Sociodemographic and hospital‐based predictors of intense end‐of‐life care among children, adolescents, and young adults with hematologic malignancies
Mun S, Wang R, Ma X, Ananth P. Sociodemographic and hospital‐based predictors of intense end‐of‐life care among children, adolescents, and young adults with hematologic malignancies. Cancer 2021, 127: 3817-3824. PMID: 34185881, PMCID: PMC8478813, DOI: 10.1002/cncr.33764.Peer-Reviewed Original ResearchConceptsHematologic malignanciesYoung adultsLife careMultivariable logistic regression modelCancer-directed treatmentPremier Healthcare DatabaseRetrospective cohort studyEmergency department visitsIntensive care unitHigh-intensity endDays of lifeMajority of childrenLogistic regression modelsIntravenous chemotherapyTracheostomy placementCohort studyDepartment visitsCare unitMechanical ventilationHospital characteristicsMultivariable modelCardiopulmonary resuscitationType of insuranceHealthcare databasesMalignancy
2020
Patterns of medication use at end of life by pediatric inpatients with cancer
Prozora S, Shabanova V, Ananth P, Pashankar F, Kupfer GM, Massaro SA, Davidoff AJ. Patterns of medication use at end of life by pediatric inpatients with cancer. Pediatric Blood & Cancer 2020, 68: e28837. PMID: 33306281, DOI: 10.1002/pbc.28837.Peer-Reviewed Original ResearchConceptsMedication usePediatric inpatientsVizient Clinical Database/Resource ManagerHematopoietic stem cell transplantLife-sustaining medicationsMedication utilization patternsSymptom management medicationsUse of opioidsStem cell transplantIntensive care unitLength of stayAcademic medical centerResource use dataLast weekWarrants further studyEvidence-based approachVasopressor useEnd of lifeCare unitCell transplantMedication categoriesResuscitate statusRetrospective studyMalignancy typeOdds ratio
2017
Medical marijuana in pediatric oncology: A review of the evidence and implications for practice
Ananth P, Reed‐Weston A, Wolfe J. Medical marijuana in pediatric oncology: A review of the evidence and implications for practice. Pediatric Blood & Cancer 2017, 65 PMID: 28926679, DOI: 10.1002/pbc.26826.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMedical MarijuanaNeoplasmsConceptsMedical marijuanaPediatric oncologyCancer-related symptomsPediatric oncology patientsSupportive care agentsMechanism of actionSupportive carePediatric patientsOncology patientsSerious illnessCare agentsPatientsOncologyMarijuanaPotential benefitsPurported benefitsFuture investigationsReviewSymptomsIllnessCancerCare