2018
Antigen-mediated regulation in monoclonal gammopathies and myeloma
Nair S, Sng J, Boddupalli CS, Seckinger A, Chesi M, Fulciniti M, Zhang L, Rauniyar N, Lopez M, Neparidze N, Parker T, Munshi NC, Sexton R, Barlogie B, Orlowski R, Bergsagel L, Hose D, Flavell RA, Mistry PK, Meffre E, Dhodapkar MV. Antigen-mediated regulation in monoclonal gammopathies and myeloma. JCI Insight 2018, 3: e98259. PMID: 29669929, PMCID: PMC5931125, DOI: 10.1172/jci.insight.98259.Peer-Reviewed Original ResearchConceptsMultiple myelomaPlasma cellsGaucher diseaseAntigenic stimulationMonoclonal gammopathyAntigen-driven stimulationMonoclonal IgClonal IgB cell receptorSingle tumor cellsPatient cohortUndetermined significanceVivo responsivenessMalignant cloneGammopathyTumor growthMonoclonal tumorsCell receptorTumor cellsAntigenGene expression profilingStimulationClonal natureMyelomaTumors
2004
Gaucher disease type 1: Revised recommendations on evaluations and monitoring for adult patients
Weinreb NJ, Aggio MC, Andersson HC, Andria G, Charrow J, Clarke JT, Erikson A, Giraldo P, Goldblatt J, Hollak C, Ida H, Kaplan P, Kolodny EH, Mistry P, Pastores GM, Pires R, Prakesh-Cheng A, Rosenbloom BE, Scott CR, Sobreira E, Tylki-Szymańska A, Vellodi A, vom Dahl S, Wappner RS, Zimran A. Gaucher disease type 1: Revised recommendations on evaluations and monitoring for adult patients. Seminars In Hematology 2004, 41: 15-22. PMID: 15468046, DOI: 10.1053/j.seminhematol.2004.07.010.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersCytogenetic AnalysisDiagnostic ImagingGaucher DiseaseHematologic TestsHumansRegistriesConceptsType 1 Gaucher diseaseAdult patientsGaucher diseaseVariable progression ratesVisceral organ involvementPatient-reported qualitySF-36 surveyComplete physical examinationSignificant clinical complicationsFamily medical historyRadiologic imaging techniquesPotential permanent disabilityOrgan involvementClinical complicationsPhysical examinationMedical historySerial monitoringSkeletal involvementTherapy dosePermanent disabilityProgression rateTreatment statusTherapeutic goalsClinical heterogeneityPatients