Human TRIM Gene Expression in Response to Interferons
Carthagena L, Bergamaschi A, Luna JM, David A, Uchil PD, Margottin-Goguet F, Mothes W, Hazan U, Transy C, Pancino G, Nisole S. Human TRIM Gene Expression in Response to Interferons. PLOS ONE 2009, 4: e4894. PMID: 19290053, PMCID: PMC2654144, DOI: 10.1371/journal.pone.0004894.Peer-Reviewed Original ResearchConceptsTRIM genesTRIM proteinsAntiviral activityGene expressionFamily of proteinsTripartite motif (TRIM) proteinsPrimary human immune cellsAntiviral immune responseGene expression analysisHuman immune cellsHost antiviral activityActivation of macrophagesMonocyte-derived macrophagesHuman primary lymphocytesMotif proteinTripartite architectureExpression analysisImmune cellsImmune responseHIV activityInnate immunityPrimate cellsGenesPrimary lymphocytesProtein