2015
Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity
Hayashi P, Fontana R, Chalasani N, Stolz A, Talwalkar J, Navarro V, Lee W, Davern T, Kleiner D, Gu J, Hoofnagle J, Investigators D, Chalasani N, Vuppalanchi R, Molleston J, Lumeng L, Corne A, Plummer A, Bonkovsky H, Protiva P, Freston J, Rosson R, Levine R, Maliakkal B, Appleton P, Smialek M, Fontana R, Conjeevaram H, Moseley R, Gordon S, Welch S, Worley J, Kridler J, Trivedi S, Kochlar S, Watkins P, Hayashi P, Russo M, Guess H, Beaver K, Smith A, Lewis J, Pusek S, Russell T, Mehltretter L, Davern T, Bonacini M, Partovi K, Fajardo K, Tai S, Lee W, Rockey D, Larson A, Grant L, Landgraf K, Stoltz A, Kaplowitz N, Milstein S, Talwalker J, Johnson S, Navarro V, Reddy R, Vega M, Wirjosemito A, Evans K, Rochon J, McHutchison J, Tilllmann H, Maggio M, Yang H, Galan K, Cosslin E, Sunas L, Collini M, Rose T, Crowder M, Scharenbroich C, Rostami H, Jiezhun S, Monroe T, Hammett A, Rosado N, Serrano J, Seeff L, Hoofnagle J, Toke D, Witt D, Higgins H, Kleiner D, Avigan M, Senior J. Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity. Clinical Gastroenterology And Hepatology 2015, 13: 1676-1682.e1. PMID: 25724701, PMCID: PMC4653068, DOI: 10.1016/j.cgh.2015.02.024.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAdverse Drug Reaction Reporting SystemsAgedAntitubercular AgentsChemical and Drug Induced Liver InjuryChildChild, PreschoolDrug-Related Side Effects and Adverse ReactionsFemaleGuideline AdherenceHealth Services ResearchHumansIsoniazidMaleMiddle AgedProspective StudiesRetrospective StudiesUnited StatesYoung AdultConceptsLiver transplantationATS guidelinesIsoniazid hepatotoxicityLeading causeATS criteriaMeeting criteriaAmerican Thoracic Society guidelinesUnderwent liver transplantationThoracic Society guidelinesSeverity Index scoreCases of hepatotoxicityLatent tuberculosisMedian ageLiver injurySociety guidelinesPoor adherenceSevere outcomesInclusion criteriaSevere casesSevere injuriesIndex scoreHepatotoxicityAbstractTextMonitoring guidelinesPatients
2008
Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug‐induced liver injury
Rochon J, Protiva P, Seeff LB, Fontana RJ, Liangpunsakul S, Watkins PB, Davern T, McHutchison JG, Network D. Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug‐induced liver injury. Hepatology 2008, 48: 1175-1183. PMID: 18798340, PMCID: PMC3618289, DOI: 10.1002/hep.22442.Peer-Reviewed Original ResearchConceptsRoussel Uclaf Causality Assessment MethodDrug-induced liver injuryCausality Assessment MethodLiver injuryDrug-induced liver injury casesDrug-Induced Liver Injury NetworkLiver injury casesCases of hepatotoxicityInterrater reliabilityStrength of associationDeviation ageCase of drugsTest-retest reliabilityTest-retest differencesCausality assessmentInjury casesInjuryFive-category scaleSame reviewersSame assessorPhenytoinReviewersIsoniazidAmoxicillinResearch settings