2015
Superion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Davis RP, Miller LE, Block JE, Geisler FH. Superion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis. Spine 2015, 40: 275-282. PMID: 25494323, DOI: 10.1097/brs.0000000000000735.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisIntermittent neurogenic claudicationInterspinous process spacerNeurogenic claudicationClinical successSpinal stenosisModerate lumbar spinal stenosisPrimary composite endpointRate of complicationsMajority of patientsInvasive treatment alternativeConservative careLeg painSurgical decompressionControl patientsMost patientsComposite endpointNonsurgical managementHigh quality comparative dataPatient complaintsNoninferiority trialBACKGROUND DATAClaudicationInterspinous spacerPatients
2011
Cement Augmentation of Refractory Osteoporotic Vertebral Compression Fractures
Gerling MC, Eubanks JD, Patel R, Whang PG, Bohlman HH, Ahn NU. Cement Augmentation of Refractory Osteoporotic Vertebral Compression Fractures. Spine 2011, 36: e1266-e1269. PMID: 21358465, DOI: 10.1097/brs.0b013e31820a0b3f.Peer-Reviewed Original ResearchConceptsOsteoporotic vertebral compression fracturesInpatient pain managementVertebral compression fracturesCement augmentationPain managementBed restCompression fracturesNumber of fracturesProportional hazards regression modelsConservative pain managementIntractable back painNational Death IndexCement augmentation proceduresHigh-energy traumaSignificant survival advantageHazards regression modelsHigh-dose narcoticsKaplan-Meier plotsUniversity Hospital databaseExact Fisher testMann-Whitney testAggressive managementConservative treatmentElderly patientsChart review
2009
The Management of Spinal Injuries in Patients With Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis
Whang PG, Goldberg G, Lawrence JP, Hong J, Harrop JS, Anderson DG, Albert TJ, Vaccaro AR. The Management of Spinal Injuries in Patients With Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis. Clinical Spine Surgery A Spine Publication 2009, 22: 77-85. PMID: 19342927, DOI: 10.1097/bsd.0b013e3181679bcb.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overComorbidityDisability EvaluationFemaleHumansHyperostosis, Diffuse Idiopathic SkeletalMaleMiddle AgedMortalityNeurosurgical ProceduresOutcome Assessment, Health CarePostoperative ComplicationsRadiographyRetrospective StudiesSpinal Cord CompressionSpinal FracturesSpinal InjuriesSpineSpondylitis, AnkylosingTreatment OutcomeConceptsDiffuse idiopathic skeletal hyperostosisIdiopathic skeletal hyperostosisSpinal injuryDISH patientsNeurologic deficitsClinical outcomesAS patientsSkeletal hyperostosisAmerican Spinal Injury Association Impairment ScaleHalo-vest orthosisOverall complication rateHalo-vest immobilizationAppropriate imaging studiesSpinal cord injurySubaxial cervical spineOdom's criteriaNonoperative treatmentComplication rateNeurologic injuryNeurologic statusASIA ARetrospective reviewOperative managementCord injurySingle institution
2007
The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study
Vaccaro AR, Whang PG, Patel T, Phillips FM, Anderson DG, Albert TJ, Hilibrand AS, Brower RS, Kurd MF, Appannagari A, Patel M, Fischgrund JS. The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study. The Spine Journal 2007, 8: 457-465. PMID: 17588821, DOI: 10.1016/j.spinee.2007.03.012.Peer-Reviewed Original ResearchConceptsOP-1 PuttyUninstrumented fusionIliac crest autograftDegenerative spondylolisthesisOverall success rateAutograft patientsX-ray filmsAdverse eventsDecompressive laminectomyCrest autograftAutogenous boneShort Form Health Survey scoresForm Health Survey scoresBone graft substituteAutogenous iliac crest bone graftIliac crest bone graftPatient-reported outcome measuresPilot studyIntermediate-term efficacyOswestry Disability IndexPreoperative Oswestry scoreHealth Survey scoresPrimary efficacy endpointSF-36 scoresSymptomatic spinal stenosis