2023
Longitudinal Comparative Analysis of Complications and Subsequent Interventions Following Stand-Alone Interspinous Spacers, Open Decompression, or Fusion for Lumbar Stenosis
Whang P, Tran O, Rosner H. Longitudinal Comparative Analysis of Complications and Subsequent Interventions Following Stand-Alone Interspinous Spacers, Open Decompression, or Fusion for Lumbar Stenosis. Advances In Therapy 2023, 40: 3512-3524. PMID: 37289411, PMCID: PMC10329952, DOI: 10.1007/s12325-023-02562-6.Peer-Reviewed Original ResearchConceptsLong-term complicationsLumbar spinal stenosisLumbar spine surgeryFirst surgical interventionLife-threatening eventsSurgical interventionISD patientsSurgery cohortOpen decompressionOpen surgerySpine surgerySubsequent interventionsComplication-related costsOpen surgery cohortSubsequent surgical interventionInterspinous spacer devicesFusion cohortLSS patientsConservative therapyBaseline characteristicsPatient agePostoperative outcomesLumbar stenosisSpinal stenosisMedicare database
2020
Evidence-Based Recommendations for Spine Surgery.
Fisher CG, Vaccaro AR, Patel AA, Whang PG, Thomas KC, Chi J, Mulpuri K, Prasad SK. Evidence-Based Recommendations for Spine Surgery. Spine 2020, 45: 851-859. PMID: 32355150, DOI: 10.1097/brs.0000000000003512.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDecompression, SurgicalFemaleHumansLumbar VertebraeLumbosacral RegionMaleMiddle AgedSpinal FusionConceptsSpine surgeryDecompression surgeryLumbar decompression surgerySpinal decompression surgeryPost-operative MRISagittal spinopelvic alignmentEvidence-based recommendationsLumbar disc arthroplastyLumbar surgeryPrognostic factorsTranexamic acidOsteoporotic patientsDisc arthroplastySpinopelvic alignmentSurgeryClinical practiceComparative effectivenessPatientsArthroplastyRecommendationsFusion supportMRI
2017
Predictors of Outcome in Conservative and Minimally Invasive Surgical Management of Pain Originating From the Sacroiliac Joint
Dengler J, Duhon B, Whang P, Frank C, Glaser J, Sturesson B, Garfin S, Cher D, Rendahl A, Polly D. Predictors of Outcome in Conservative and Minimally Invasive Surgical Management of Pain Originating From the Sacroiliac Joint. Spine 2017, 42: 1664-1673. PMID: 28350586, PMCID: PMC5636200, DOI: 10.1097/brs.0000000000002169.Peer-Reviewed Original ResearchConceptsOswestry Disability IndexPredictors of outcomeSIJ fusionVisual analog scaleInvasive surgical managementSacroiliac jointSIJ painTreatment outcomesConservative managementProspective trialSurgical managementSingle-arm prospective trialInvasive SIJ fusionLonger pain durationLower patient ageInvasive surgical treatmentIndividual patient dataPatient-level analysisTriangular titanium implantsBetter treatment outcomesAnalysis of predictorsRandom-effects modelMultivariate regression analysisTrial sample sizeNonopioid users
2015
Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs Nonsurgical Management for Sacroiliac Joint Dysfunction: 12-Month Outcomes
Polly DW, Cher DJ, Wine KD, Whang PG, Frank CJ, Harvey CF, Lockstadt H, Glaser JA, Limoni RP, Sembrano JN. Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs Nonsurgical Management for Sacroiliac Joint Dysfunction: 12-Month Outcomes. Neurosurgery 2015, 77: 674-691. PMID: 26291338, PMCID: PMC4605280, DOI: 10.1227/neu.0000000000000988.Peer-Reviewed Original ResearchConceptsTriangular titanium implantsQuality of lifeSacroiliac joint dysfunctionSurgical groupNonsurgical managementSIJ dysfunctionSIJ fusionJoint dysfunctionOswestry Disability Index improvementSix-month success rateInvasive Sacroiliac Joint FusionChronic SIJ dysfunctionInvasive SIJ fusionNonsurgical management groupsOswestry Disability IndexSacroiliac joint fusionLow back painRandomized Controlled TrialsLevel 1 studiesSuccess rateTitanium implantsDegenerative sacroiliitisSIJ disruptionDisability IndexSIJ pain
2014
Evidence-Based Recommendations for Spine Surgery
Vaccaro AR, Fisher CG, Whang PG, Patel AA, Thomas KC, Mulpuri K, Chi J, Prasad SK. Evidence-Based Recommendations for Spine Surgery. Spine 2014, 39: e1183-e1189. PMID: 25166476, DOI: 10.1097/brs.0000000000000492.Peer-Reviewed Original Research
2013
Comparison of Axial and Anterior Interbody Fusions of the L5–S1 Segment
Whang PG, Sasso RC, Patel VV, Ali RM, Fischgrund JS. Comparison of Axial and Anterior Interbody Fusions of the L5–S1 Segment. Clinical Spine Surgery A Spine Publication 2013, 26: 437-443. PMID: 24196923, DOI: 10.1097/bsd.0b013e318292aad7.Peer-Reviewed Original ResearchConceptsAnterior lumbar interbody fusionAdverse eventsInterbody fusionPosterior fixationDevice-related adverse eventsL5-S1 interbody fusionL5-S1 disc spaceAnterior interbody fusionAnterior retroperitoneal approachSerious intraoperative complicationsAnterior column supportDifferent surgical approachesLumbar interbody fusionRadiographic fusion rateL5-S1 segmentSupplemental posterior fixationAxiaLIF techniqueHospital chartsIntraoperative complicationsMulticenter reviewRadiographic successRetroperitoneal approachArthrodesis ratesPresacral spaceProcedural dataRecovery Room Radiographs Not Found to Have Incremental Utility Above Intraoperative Images After Lumbar Fusion Procedures
Bohl DD, Gruskay JA, Miller CP, Varthi A, Ruiz FK, Whang PG, Grauer JN. Recovery Room Radiographs Not Found to Have Incremental Utility Above Intraoperative Images After Lumbar Fusion Procedures. Spine 2013, 38: 1927-1933. PMID: 23883831, DOI: 10.1097/brs.0b013e3182a527be.Peer-Reviewed Original ResearchConceptsLumbar fusion proceduresLumbar interbody fusionClinical utilityRecovery roomInterbody fusionFusion proceduresSurgical constructTransforaminal lumbar interbody fusionAnterior lumbar interbody fusionAnterior-posterior fusionRetrospective case seriesPosterolateral lumbar fusionLow clinical utilityPlain film imagesRecovery room radiographsIntraoperative imagesIncremental clinical utilityCase seriesConsecutive seriesLumbar fusionBACKGROUND DATAIntraoperative fluoroscopic imagesWound closureRadiation exposureIncremental utilityMitigating Adverse Event Reporting Bias in Spine Surgery
Auerbach JD, McGowan KB, Halevi M, Gerling MC, Sharan AD, Whang PG, Maislin G. Mitigating Adverse Event Reporting Bias in Spine Surgery. Journal Of Bone And Joint Surgery 2013, 95: 1450-1456. PMID: 23965694, DOI: 10.2106/jbjs.l.00251.Peer-Reviewed Original ResearchConceptsIndependent clinical events committeeClinical events committeeAdverse eventsClinical trialsLevels of severityInvestigational device exemption studyFuture clinical trialsAdverse event dataLumbar spinal fusionAdverse event reportingAdverse event reportsSpinal stenosisEvents committeeSafety profileSurgery StudyFusion groupInvestigator biasSpine surgerySpinal fusionSpine surgeonsSurgeryInvestigational deviceStudy sponsorEvent reportingFinancial interestsComplications Associated With the Use of the Recombinant Human Bone Morphogenetic Proteins for Posterior Interbody Fusions of the Lumbar Spine
Chrastil J, Low JB, Whang PG, Patel AA. Complications Associated With the Use of the Recombinant Human Bone Morphogenetic Proteins for Posterior Interbody Fusions of the Lumbar Spine. Spine 2013, 38: e1020-e1027. PMID: 23629484, DOI: 10.1097/brs.0b013e3182982f8e.Peer-Reviewed Original ResearchEvidence-Based Recommendations for Spine Surgery
Vaccaro AR, Fisher CG, Patel AA, Prasad SK, Chi J, Mulpuri K, Thomas KC, Whang PG. Evidence-Based Recommendations for Spine Surgery. Spine 2013, 38: e970-e978. PMID: 23629483, DOI: 10.1097/brs.0b013e3182982d32.Peer-Reviewed Original ResearchLumbar spinal stenosis.
Lee JY, Whang PG, Lee JY, Phillips FM, Patel AA. Lumbar spinal stenosis. Instructional Course Lectures 2013, 62: 383-96. PMID: 23395043.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisSpinal stenosisNonsurgical treatment optionsOptimal treatment approachEvidence-based outcomesTreatment optionsDiagnostic workupPatient presentationSpinal surgeryCommon reasonElderly populationTreatment approachesSurgical innovationStenosisPatientsSurgeryPathophysiologyWorkupDiseaseDiagnosis
2012
Evidence-Based Recommendations for Spine Surgery
Vaccaro AR, Fisher CG, Angevine PD, Patel AA, Mulpuri K, Thomas KC, Whang PG, Prasad SK. Evidence-Based Recommendations for Spine Surgery. Spine 2012, 37: e875-e882. PMID: 22751143, DOI: 10.1097/brs.0b013e3182454ef0.Peer-Reviewed Original ResearchThe Efficacies of 2 Ceramic Bone Graft Extenders for Promoting Spinal Fusion in a Rabbit Bone Paucity Model
Miller CP, Jegede K, Essig D, Garg H, Bible JE, Biswas D, Whang PG, Grauer JN. The Efficacies of 2 Ceramic Bone Graft Extenders for Promoting Spinal Fusion in a Rabbit Bone Paucity Model. Spine 2012, 37: 642-647. PMID: 21857402, DOI: 10.1097/brs.0b013e31822e604e.Peer-Reviewed Original Research
2011
A novel technique for preparing an allograft fibula for use as a transsacral graft as treatment for high-grade spondylolisthesis.
Milewski MD, Whang PG, Grauer JN. A novel technique for preparing an allograft fibula for use as a transsacral graft as treatment for high-grade spondylolisthesis. The American Journal Of Orthopedics 2011, 40: 130-3, 138. PMID: 21738906.Peer-Reviewed Original ResearchConceptsAnterior cruciate ligamentInstrumented posterolateral fusionFibular allograftPosterolateral fusionHigh-grade spondylolisthesisAllograft fibulaIndex surgerySixth patientAdverse eventsIntraoperative complicationsProminent hardwareCruciate ligamentAllograftsPatientsS1 segmentPosterior implantationDeformityReamerL5ComplicationsSpondylolisthesisSurgeryGraftIleumYears
2009
Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model.
Miller CP, Simpson AK, Whang PG, Erickson BP, Waked WR, Lawrence JP, Grauer JN. Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model. The American Journal Of Orthopedics 2009, 38: 578-84. PMID: 20049353.Peer-Reviewed Original ResearchConceptsLocal infectionRecombinant human bone morphogenetic proteinEarly deathRabbit posterolateral lumbar fusion modelPosterolateral lumbar fusion modelRhBMP-2Postoperative infectionSurgical infectionsSpine surgeryAutograft groupSpinal arthrodesisSterile salineFusion rateAutograftRecombinant human bone morphogenetic protein-2InfectionHuman bone morphogenetic proteinHuman bone morphogenetic protein-2Bone formationProtein 2Staphylococcus aureusRabbitsBone morphogenetic protein-2Bone morphogenetic proteinMorphogenetic protein-2
2008
Pseudarthrosis following lumbar interbody fusion using bone morphogenetic protein-2: intraoperative and histopathologic findings.
Whang PG, O'Hara BJ, Ratliff J, Sharan A, Brown Z, Vaccaro AR. Pseudarthrosis following lumbar interbody fusion using bone morphogenetic protein-2: intraoperative and histopathologic findings. Orthopedics 2008, 31 PMID: 19226004, DOI: 10.3928/01477447-20110525-20.Peer-Reviewed Original ResearchPostoperative bracing after spine surgery for degenerative conditions: a questionnaire study
Bible JE, Biswas D, Whang PG, Simpson AK, Rechtine GR, Grauer JN. Postoperative bracing after spine surgery for degenerative conditions: a questionnaire study. The Spine Journal 2008, 9: 309-316. PMID: 18790685, DOI: 10.1016/j.spinee.2008.06.453.Peer-Reviewed Original ResearchConceptsSpine surgeonsPostoperative bracingSpinal proceduresSpecific spinal proceduresVariety of orthosesCervical spine proceduresAnterior cervical spineInstrumented lumbar fusionSingle-page questionnaireDuration of treatmentType of orthosisSpecific surgical proceduresQuestionnaire studyInternal fixationLumbar fusionCervical spineSpine surgeryClinical studiesSpine proceduresBracing protocolSurgical proceduresLumbar spineCommon reasonProper indicationsClinical experienceFinancial Incentives for Lumbar Surgery: A Critical Analysis of Physician Reimbursement for Decompression and Fusion Procedures
Whang PG, Lim MR, Sasso RC, Skelton A, Brown ZB, Anderson D, Albert TJ, Hilibrand AS, Vaccaro AR. Financial Incentives for Lumbar Surgery: A Critical Analysis of Physician Reimbursement for Decompression and Fusion Procedures. Clinical Spine Surgery A Spine Publication 2008, 21: 381-386. PMID: 18679090, DOI: 10.1097/bsd.0b013e31814d4e1b.Peer-Reviewed Original ResearchConceptsInstrumented fusion proceduresFusion proceduresIsolated decompressionAutogenous iliac crest boneSingle-level decompressionIliac crest boneLumbar degenerative conditionsLumbar decompressionLumbar surgeryPostoperative visitDecompression groupSingle surgeonConsecutive seriesOffice chartsOperative reportsPosterolateral fusionSurgical timeTotal clinical timeCrest boneLumbar degenerationSpinal fusionBACKGROUND DATALumbar arthrodesisType of operationSpine surgeonsThoracolumbar fractures: anterior decompression and interbody fusion.
Whang PG, Vaccaro AR. Thoracolumbar fractures: anterior decompression and interbody fusion. Journal Of The American Academy Of Orthopaedic Surgeons 2008, 16: 424-31. PMID: 18612000, DOI: 10.5435/00124635-200807000-00008.Peer-Reviewed Original Research
2007
Clinical applications of BMP-7/OP-1 in fractures, nonunions and spinal fusion
White AP, Vaccaro AR, Hall JA, Whang PG, Friel BC, McKee MD. Clinical applications of BMP-7/OP-1 in fractures, nonunions and spinal fusion. International Orthopaedics 2007, 31: 735-741. PMID: 17962946, PMCID: PMC2266670, DOI: 10.1007/s00264-007-0422-x.Peer-Reviewed Original ResearchConceptsBone morphogenetic protein-7Tibial fracturesSpinal fusionOP-1Bony fusion massDistal tibial fracturesLong bone nonunionOpen tibial fracturesRoute of administrationFuture clinical investigationsUse of BMPLong bone applicationsRecombinant human OP-1Collagen matrix resultsSupportive evidenceScaphoid nonunionClinical outcomesTibial nonunionClinical trialsClinical studiesBone nonunionClinical investigationNew therapeutic applicationsAnimal modelsMorphogenetic protein-7