2023
Quantifying the Long-Term Impact of a Motion-Sparing Interspinous Spacer on Sagittal Alignment in Patients with Lumbar Spinal Stenosis
Whang P, Chen L, Jain R. Quantifying the Long-Term Impact of a Motion-Sparing Interspinous Spacer on Sagittal Alignment in Patients with Lumbar Spinal Stenosis. Interventional Pain Medicine 2023, 2: 100236. DOI: 10.1016/j.inpm.2023.100236.Peer-Reviewed Original Research
2020
Evidence-Based Recommendations for Spine Surgery.
Fisher CG, Vaccaro AR, Patel AA, Whang PG, Thomas KC, Chi J, Mulpuri K, Prasad SK. Evidence-Based Recommendations for Spine Surgery. Spine 2020, 45: 851-859. PMID: 32355150, DOI: 10.1097/brs.0000000000003512.Peer-Reviewed Original ResearchConceptsSpine surgeryDecompression surgeryLumbar decompression surgerySpinal decompression surgeryPost-operative MRISagittal spinopelvic alignmentEvidence-based recommendationsLumbar disc arthroplastyLumbar surgeryPrognostic factorsTranexamic acidOsteoporotic patientsDisc arthroplastySpinopelvic alignmentSurgeryClinical practiceComparative effectivenessPatientsArthroplastyRecommendationsFusion supportMRILoss of nucleus accumbens low-frequency fluctuations is a signature of chronic pain
Makary MM, Polosecki P, Cecchi GA, DeAraujo IE, Barron DS, Constable TR, Whang PG, Thomas DA, Mowafi H, Small DM, Geha P. Loss of nucleus accumbens low-frequency fluctuations is a signature of chronic pain. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 10015-10023. PMID: 32312809, PMCID: PMC7211984, DOI: 10.1073/pnas.1918682117.Peer-Reviewed Original ResearchConceptsChronic low back pain patientsLow back pain patientsChronic painPain patientsChronic phaseChronic back pain patientsBack pain patientsRostral anterior cingulate cortexAnterior cingulate cortexAdditional independent datasetsRisk of transitionResting-state activityPersistent painBack painAccumbens volumeHealthy controlsNucleus accumbensPainSeparate cohortPatientsCingulate cortexPrevalent diseaseFunctional connectivityLoss of nucleiSubcortical signatures
2018
Lumbar Disc Herniation: A Controlled, Prospective Study with 10 Years of Observation
Gala R, Whang P. Lumbar Disc Herniation: A Controlled, Prospective Study with 10 Years of Observation. 2018, 109-112. DOI: 10.1201/9781315154053-21.Peer-Reviewed Original ResearchLumbar disc herniationGroup of patientsDisc herniationNonoperative treatmentInitial nonoperative treatmentLumbar disc prolapseLong-term outcomesTiming of treatmentObservational armConservative managementSurgical treatmentDisc prolapseProspective studyRetrospective natureCommon causeNatural historyHerniationDiagnostic imagingPatientsDefinitive indicationTreatmentSelection biasYears of observationGroupPrior studies
2017
Interspinous implants to treat spinal stenosis
Gala RJ, Russo GS, Whang PG. Interspinous implants to treat spinal stenosis. Current Reviews In Musculoskeletal Medicine 2017, 10: 182-188. PMID: 28324328, PMCID: PMC5435644, DOI: 10.1007/s12178-017-9413-8.Peer-Reviewed Original ResearchSpinal stenosisInterspinous spacerModerate spinal stenosisOpen decompressive surgeryLumbar spinal stenosisPedicle screw instrumentationFormal decompressionSuperion deviceDecompressive surgerySignificant morbidityPatient selectionInvasive optionInvasive strategyImproved outcomesInterspinous implantStenosisDecompressionInterspinous spaceSpinal anatomyCoflex deviceOutcomesImplantsMorbidityComplicationsPatients
2015
Superion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Davis RP, Miller LE, Block JE, Geisler FH. Superion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis. Spine 2015, 40: 275-282. PMID: 25494323, DOI: 10.1097/brs.0000000000000735.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisIntermittent neurogenic claudicationInterspinous process spacerNeurogenic claudicationClinical successSpinal stenosisModerate lumbar spinal stenosisPrimary composite endpointRate of complicationsMajority of patientsInvasive treatment alternativeConservative careLeg painSurgical decompressionControl patientsMost patientsComposite endpointNonsurgical managementHigh quality comparative dataPatient complaintsNoninferiority trialBACKGROUND DATAClaudicationInterspinous spacerPatients
2014
Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Miller LE, Block JE, Geisler FH. Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis. BMC Musculoskeletal Disorders 2014, 15: 221. PMID: 24996648, PMCID: PMC4109165, DOI: 10.1186/1471-2474-15-221.Peer-Reviewed Original ResearchMeSH KeywordsAgedBack PainDisability EvaluationEquipment DesignFemaleHumansLumbar VertebraeMaleOrthopedic ProceduresPain MeasurementPain, PostoperativePatient SatisfactionPredictive Value of TestsProspective StudiesRadiographyRecovery of FunctionSpinal StenosisSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesConceptsModerate lumbar spinal stenosisLumbar spinal stenosisConservative careInterspinous spacerClinical outcomesSpinal stenosisBack functionTwo-year clinical outcomesOswestry Disability IndexPhysical function scoresPatient-reported outcomesInvasive surgical alternativePatient satisfaction scoresExtremity painAxial painDisability IndexComplication dataFunction scoresSurgical alternativePatientsSatisfaction scoresSymptom severityPainIndex levelMulticenter
2013
Lumbar spinal stenosis.
Lee JY, Whang PG, Lee JY, Phillips FM, Patel AA. Lumbar spinal stenosis. Instructional Course Lectures 2013, 62: 383-96. PMID: 23395043.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisSpinal stenosisNonsurgical treatment optionsOptimal treatment approachEvidence-based outcomesTreatment optionsDiagnostic workupPatient presentationSpinal surgeryCommon reasonElderly populationTreatment approachesSurgical innovationStenosisPatientsSurgeryPathophysiologyWorkupDiseaseDiagnosis
2011
A novel technique for preparing an allograft fibula for use as a transsacral graft as treatment for high-grade spondylolisthesis.
Milewski MD, Whang PG, Grauer JN. A novel technique for preparing an allograft fibula for use as a transsacral graft as treatment for high-grade spondylolisthesis. The American Journal Of Orthopedics 2011, 40: 130-3, 138. PMID: 21738906.Peer-Reviewed Original ResearchConceptsAnterior cruciate ligamentInstrumented posterolateral fusionFibular allograftPosterolateral fusionHigh-grade spondylolisthesisAllograft fibulaIndex surgerySixth patientAdverse eventsIntraoperative complicationsProminent hardwareCruciate ligamentAllograftsPatientsS1 segmentPosterior implantationDeformityReamerL5ComplicationsSpondylolisthesisSurgeryGraftIleumYears
2008
Coccydynia
Patel R, Appannagari A, Whang PG. Coccydynia. Current Reviews In Musculoskeletal Medicine 2008, 1: 223. PMID: 19468909, PMCID: PMC2682410, DOI: 10.1007/s12178-008-9028-1.Peer-Reviewed Original ResearchChronic inflammatory processGold standard treatmentConservative modalitiesNonsurgical managementDynamic radiographsSurgical interventionStandard treatmentInflammatory processLocal injectionPostural adjustmentsCoccydyniaPatientsAbnormal mobilityGreater improvementCoccyxMost casesPainCoccygectomyAnestheticsMassageRadiographsSteroidsDegeneration
2007
P64. The Initial Assessment and Early Management of Spine Fractures in Patients with Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis: A Comparison of Treatment Methods
Whang P, Goldberg G, Brown Z, Sanfilippo J, Anderson G, Albert T, Hilibrand A, Vaccaro A. P64. The Initial Assessment and Early Management of Spine Fractures in Patients with Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis: A Comparison of Treatment Methods. The Spine Journal 2007, 7: 112s. DOI: 10.1016/j.spinee.2007.07.270.Peer-Reviewed Original ResearchThe Influence of Fracture Mechanism and Morphology on the Reliability and Validity of Two Novel Thoracolumbar Injury Classification Systems
Whang PG, Vaccaro AR, Poelstra KA, Patel AA, Anderson DG, Albert TJ, Hilibrand AS, Harrop JS, Sharan AD, Ratliff JK, Hurlbert RJ, Anderson P, Aarabi B, Sekhon LH, Gahr R, Carrino JA. The Influence of Fracture Mechanism and Morphology on the Reliability and Validity of Two Novel Thoracolumbar Injury Classification Systems. Spine 2007, 32: 791-795. PMID: 17414915, DOI: 10.1097/01.brs.0000258882.96011.47.Peer-Reviewed Original ResearchConceptsThoracolumbar Injury Severity ScoreThoracolumbar fracturesSeverity scoreThoracolumbar injuriesInjury mechanismSubstantial reproducibilityInjury Severity ScoreMechanism of traumaThoracolumbar Injury Classification SystemThoracolumbar Injury ClassificationInjury classification systemGroup of surgeonsTLISS systemInjury characteristicsRadiographic findingsInjury classificationSpinal traumaBACKGROUND DATAInjury morphologySpinal stabilityPosterior ligamentsPatientsInjuryRespective kappa valuesKappa statisticsThe Adoption of a New Classification System
Patel AA, Vaccaro AR, Albert TJ, Hilibrand AS, Harrop JS, Anderson DG, Sharan A, Whang PG, Poelstra KA, Arnold P, Dimar J, Madrazo I, Hegde S. The Adoption of a New Classification System. Spine 2007, 32: e105-e110. PMID: 17268253, DOI: 10.1097/01.brs.0000254107.57551.8a.Peer-Reviewed Original ResearchConceptsThoracolumbar Injury ClassificationTLISS systemConsecutive patientsInjury classificationMagnetic resonance imagingThoracolumbar injuriesInterobserver reliabilityPlain radiographsSeverity scoreResonance imagingUnweighted Cohen kappa coefficientSingle training institutionProspective clinical assessmentSpearman correlation valuesInjury classification systemAssessment timeTime-dependent changesClassification systemClinical assessmentCohen's kappa coefficientBACKGROUND DATANew classification systemPatientsSecond assessmentInjury
2006
Pharmacologic Neuroprotection in Patients with Spinal Cord Injury and the Efficacy of Early Decompressive Surgery
Poelstra K, Vaccaro A, Rao S, Patel A, Whang P, Kurd M, Stock G. Pharmacologic Neuroprotection in Patients with Spinal Cord Injury and the Efficacy of Early Decompressive Surgery. Topics In Spinal Cord Injury Rehabilitation 2006, 12: 63-76. DOI: 10.1310/c73a-3uac-8dff-h3vu.Peer-Reviewed Original ResearchAnimal models of spine fusion and low back pain
Poelstra K, Austin L, Zaslavsky J, Whang P, Patel A. Animal models of spine fusion and low back pain. Current Orthopaedic Practice 2006, 17: 214-221. DOI: 10.1097/01.bco.0000223529.57395.b8.Peer-Reviewed Original ResearchAnimal modelsCircumferential spinal fusionLow back painNew treatment strategiesReviews animal modelsBasic science advancesIntervertebral disc degenerationProgressive diseaseBack painTreatment strategiesSpinal fusionSpine fusionImproved careSurgical solutionPatient careDisc degenerationPainCarePivotal roleOsteoinductive agentsWide spectrumPatientsDegenerationDiseaseSurgeons