2020
P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study
Daffner S, Bunch J, An H, Burton D, Milam R, Park D, Strenge K, Whang P. P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study. The Spine Journal 2020, 20: s204. DOI: 10.1016/j.spinee.2020.05.520.Peer-Reviewed Original ResearchIliac crest bone graftFusion rateBone graft substituteClinical outcomesSpinal fusionOswestry Disability Index scoresProspective multicenter cohort studyAutologous iliac crest bone graftSTUDY DESIGN/SETTINGIndependent core labPosterolateral lumbar spinal fusionSF-36v2 PCSDisability Index scoresMulticenter cohort studyPosterolateral lumbar fusion surgeryProspective multicenter studyBetter clinical outcomesLumbar fusion surgeryCrest bone graftGold standard graft materialLumbar spinal fusionDESIGN/SETTINGStandard graft materialPosterolateral spinal fusionEndogenous growth factors
2007
The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study
Vaccaro AR, Whang PG, Patel T, Phillips FM, Anderson DG, Albert TJ, Hilibrand AS, Brower RS, Kurd MF, Appannagari A, Patel M, Fischgrund JS. The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study. The Spine Journal 2007, 8: 457-465. PMID: 17588821, DOI: 10.1016/j.spinee.2007.03.012.Peer-Reviewed Original ResearchConceptsOP-1 PuttyUninstrumented fusionIliac crest autograftDegenerative spondylolisthesisOverall success rateAutograft patientsX-ray filmsAdverse eventsDecompressive laminectomyCrest autograftAutogenous boneShort Form Health Survey scoresForm Health Survey scoresBone graft substituteAutogenous iliac crest bone graftIliac crest bone graftPatient-reported outcome measuresPilot studyIntermediate-term efficacyOswestry Disability IndexPreoperative Oswestry scoreHealth Survey scoresPrimary efficacy endpointSF-36 scoresSymptomatic spinal stenosis