2021
Brain Structure and Function of Chronic Low Back Pain Patients on Long-Term Opioid Analgesic Treatment: A Preliminary Study
Murray K, Lin Y, Makary MM, Whang PG, Geha P. Brain Structure and Function of Chronic Low Back Pain Patients on Long-Term Opioid Analgesic Treatment: A Preliminary Study. Molecular Pain 2021, 17: 1744806921990938. PMID: 33567986, PMCID: PMC7883154, DOI: 10.1177/1744806921990938.Peer-Reviewed Original ResearchConceptsChronic low back painOpioid analgesicsCLBP patientsPain patientsChronic low back pain patientsLow back pain patientsBrain structuresOpioid analgesic treatmentBack pain patientsClasses of medicationsChronic pain patientsLow back painLong-term riskAltered brain structureSub-cortical areasOverall significant decreaseEvidence of misuseAnalgesic treatmentChronic treatmentBack painFunctional brain imagingLimbic areasUnmedicated patientsHealthy controlsNucleus accumbens
2016
Two-Year Outcomes from a Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion vs. Non-Surgical Management for Sacroiliac Joint Dysfunction.
Polly DW, Swofford J, Whang PG, Frank CJ, Glaser JA, Limoni RP, Cher DJ, Wine KD, Sembrano JN. Two-Year Outcomes from a Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion vs. Non-Surgical Management for Sacroiliac Joint Dysfunction. The International Journal Of Spine Surgery 2016, 10: 28. PMID: 27652199, PMCID: PMC5027818, DOI: 10.14444/3028.Peer-Reviewed Original ResearchSubstantial clinical benefitNon-surgical treatmentSacroiliac joint dysfunctionTriangular titanium implantsClinical improvementMonth 24Clinical benefitSIJ painNSM groupSIJ dysfunctionJoint dysfunctionChronic low back painInvasive Sacroiliac Joint FusionChronic SIJ dysfunctionUnderwent revision surgeryNon-surgical managementTwo-Year OutcomesSacroiliac joint fusionLow back painProportion of subjectsQuality of lifeODI scoresSIJ fusionPain scoresSurgery group