The Role of Parvovirus B19 in Aplastic Crisis and Erythema Infectiosum (Fifth Disease)
Chorba T, Coccia P, Holman R, Tattersall P, Anderson L, Sudman J, Young N, Kurczynski E, Saarinen U, Moir R, Lawrence D, Jason J, Evatt B. The Role of Parvovirus B19 in Aplastic Crisis and Erythema Infectiosum (Fifth Disease). The Journal Of Infectious Diseases 1986, 154: 383-393. PMID: 3016109, DOI: 10.1093/infdis/154.3.383.Peer-Reviewed Original ResearchConceptsErythema infectiosumAplastic crisisParvovirus B19B19-specific IgMSecondary attack rateSimultaneous outbreaksThroat garglesB19 infectionClinical entityRecent infectionAsymptomatic infectionSusceptible contactsPatientsInfectionB19Attack rateSerumComparison groupIgMHousehold membersOutbreakGargleEpidemiologyUrineHuman parvovirus B19-induced epidemic acute red cell aplasia in patients with hereditary hemolytic anemia.
Saarinen U, Chorba T, Tattersall P, Young N, Anderson L, Palmer E, Coccia P. Human parvovirus B19-induced epidemic acute red cell aplasia in patients with hereditary hemolytic anemia. Blood 1986, 67: 1411-7. PMID: 3008891, DOI: 10.1182/blood.v67.5.1411.bloodjournal6751411.Peer-Reviewed Original ResearchConceptsRed cell aplasiaAcute-phase seraHuman parvovirus B19Cell aplasiaHemolytic anemiaHereditary hemolytic anemiaParvovirus B19B19-specific IgMHemoglobin SC diseaseDays of presentationB19-specific IgGParvovirus B19 DNASickle cell anemiaHuman parvovirus B19 DNAErythroid colony formationAbdominal symptomsSevere reticulocytopeniaAcute onsetAdditional patientsProdromal symptomsSC diseaseB19 DNAViremic seraPatientsCell anemia