2003
Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis
Shepard K, Gerber A, Jambhekar A, Takizawa P, Brown P, Herschlag D, DeRisi J, Vale R. Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 11429-11434. PMID: 13679573, PMCID: PMC208774, DOI: 10.1073/pnas.2033246100.Peer-Reviewed Original ResearchConceptsDNA microarray analysisBud tipRNA transportMRNA localizationMicroarray analysisCell wall maintenanceCytoplasmic mRNA transportCytoplasmic mRNA localizationAsymmetric localizationMRNA transportYeast SaccharomycesRNA reportersProtein activityUntranslated regionCell asymmetryStress responseSecondary screenYeastMRNAProteinLocalizationShe2pMetazoansMyo4pShe3p
2000
Plasma Membrane Compartmentalization in Yeast by Messenger RNA Transport and a Septin Diffusion Barrier
Takizawa P, DeRisi J, Wilhelm J, Vale R. Plasma Membrane Compartmentalization in Yeast by Messenger RNA Transport and a Septin Diffusion Barrier. Science 2000, 290: 341-344. PMID: 11030653, DOI: 10.1126/science.290.5490.341.Peer-Reviewed Original ResearchMeSH KeywordsActomyosinBiological TransportCell CompartmentationCell CycleCell Cycle ProteinsCell MembraneCytoskeletal ProteinsDiffusionDNA-Binding ProteinsFungal ProteinsMembrane ProteinsMutationMyosin Heavy ChainsMyosin Type VMyosinsOligonucleotide Array Sequence AnalysisRecombinant Fusion ProteinsRepressor ProteinsRNA, FungalRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTemperatureTranscription FactorsConceptsPlasma membrane compartmentalizationCell fate determinationMembrane diffusion barrierMother-bud neckProtein-encoding mRNAsPlasma membrane compartmentMessenger RNA transportDNA microarray analysisCell polarityFate determinationMembrane compartmentalizationAsymmetric localizationBud tipMembrane compartmentsCellular processesRNA transportMother cellsMRNA localizationMicroarray analysisYeastEpithelial cellsProteinKey roleCellsLocalization
1997
Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast
Takizawa P, Sil A, Swedlow J, Herskowitz I, Vale R. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature 1997, 389: 90-93. PMID: 9288973, DOI: 10.1038/38015.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnaphaseBase SequenceBiological TransportCell DivisionCytoskeletonDNA-Binding ProteinsFungal ProteinsGene DeletionIn Situ Hybridization, FluorescenceMicroscopy, FluorescenceRepressor ProteinsRNA, FungalRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsConceptsCell fate determinantsASH1 mRNACell fateDaughter budsActin cytoskeletonMating-type switchingMother-bud neckActin-dependent localizationMulticellular eukaryotesHigher eukaryotesRNA localizationCell cortexMRNA particlesCytoplasmic localizationAsymmetric distributionUntranslated regionActin filamentsMessenger RNADistal tipEukaryotesCytoskeletonMRNAYeastRNADaughter nuclei