Depression and/or PTSD Comorbidity Affects Response to Antidepressants in Those With Alcohol Use Disorder
Na PJ, Ralevski E, Jegede O, Wolfgang A, Petrakis IL. Depression and/or PTSD Comorbidity Affects Response to Antidepressants in Those With Alcohol Use Disorder. Frontiers In Psychiatry 2022, 12: 768318. PMID: 35058816, PMCID: PMC8765227, DOI: 10.3389/fpsyt.2021.768318.Peer-Reviewed Original ResearchPost-traumatic stress disorderAlcohol use disorderCo-occurring depressionHeavy drinking daysBetter drinking outcomesDrinking daysDiagnostic groupsDrinking outcomesDepressive symptomsUse disordersPercent heavy drinking daysPercent drinking daysRandomized control trialSerotonergic antidepressantsPTSD comorbidityControl trialDepression groupDepressive outcomesSignificant interactionOverall significant differenceDesipramineParoxetinePlaceboMedicationsComorbid MDD