2009
Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humans
MORGAN PT, KEHNE JH, SPRENGER KJ, MALISON RT. Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humans. Journal Of Sleep Research 2009, 19: 157-164. PMID: 19682231, DOI: 10.1111/j.1365-2869.2009.00757.x.Peer-Reviewed Original ResearchConceptsTotal sleep timeSleep timeMotor learningSleep-dependent motor learningRapid eye movement (REM) sleepLonger total sleep timeGamma-aminobutyric acid receptor complexEye movement sleepREM onset latencyHealthy male subjectsStage 2 sleepMemory consolidationRetrograde effectsTriazolam conditionZolpidem conditionSkill memory consolidationMovement sleepSleep-dependent memory consolidationSufficient dosesHealthy peopleSleep laboratoryPlacebo conditionBenzodiazepine siteOnset latencyMale subjects
2008
Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence
Morgan PT, Malison RT. Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence. The American Journal Of Drug And Alcohol Abuse 2008, 34: 692-702. PMID: 18850496, DOI: 10.1080/00952990802308221.Peer-Reviewed Original ResearchConceptsSleep-dependent learningCocaine-dependent personsEffects of lorazepamCognitive effectsCognitive functionMotor learningTotal sleep timeDependent learningImpulsivitySlow-wave sleepCocaine abstinenceSleep latencyAbstinenceSleep timeSleepDependent personsLearningLight sleepCognitionCocaine administrationSedative hypnoticsPilot studyLorazepamParticipantsDifferent GABA