2010
Normalizing Effects of Modafinil on Sleep in Chronic Cocaine Users
Morgan PT, Pace-Schott E, Pittman B, Stickgold R, Malison RT. Normalizing Effects of Modafinil on Sleep in Chronic Cocaine Users. American Journal Of Psychiatry 2010, 167: 331-340. PMID: 20080983, PMCID: PMC5857958, DOI: 10.1176/appi.ajp.2009.09050613.Peer-Reviewed Original ResearchMeSH KeywordsAdultBenzhydryl CompoundsCentral Nervous System StimulantsCocaineCocaine-Related DisordersDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleHumansMaleMiddle AgedModafinilPolysomnographySleep Wake DisordersSubstance Abuse Treatment CentersSubstance Withdrawal SyndromeWakefulnessConceptsMultiple sleep latency testSlow-wave sleep timeSleep latency testEffects of modafinilTotal sleep timeSleep latencyCocaine-dependent participantsSleep timeChronic cocaine usersDaytime sleepinessLatency testCocaine usersShorter REM sleep latencyDaytime sleep latencyLonger total sleep timeREM sleep latencySubjective daytime sleepinessSleep architecture variablesPolysomnographic sleep recordingsSleep architectureNocturnal sleepHealthy comparison participantsAbstinent cocaine usersDay 1Day 2
2009
Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humans
MORGAN PT, KEHNE JH, SPRENGER KJ, MALISON RT. Retrograde effects of triazolam and zolpidem on sleep‐dependent motor learning in humans. Journal Of Sleep Research 2009, 19: 157-164. PMID: 19682231, DOI: 10.1111/j.1365-2869.2009.00757.x.Peer-Reviewed Original ResearchConceptsTotal sleep timeSleep timeMotor learningSleep-dependent motor learningRapid eye movement (REM) sleepLonger total sleep timeGamma-aminobutyric acid receptor complexEye movement sleepREM onset latencyHealthy male subjectsStage 2 sleepMemory consolidationRetrograde effectsTriazolam conditionZolpidem conditionSkill memory consolidationMovement sleepSleep-dependent memory consolidationSufficient dosesHealthy peopleSleep laboratoryPlacebo conditionBenzodiazepine siteOnset latencyMale subjects