Dermatologic Changes Induced by Repeated Ixodes scapularis Bites and Implications for Prevention of Tick-Borne Infection
Krause PJ, Grant-Kels JM, Tahan SR, Dardick KR, Alarcon-Chaidez F, Bouchard K, Visini C, Deriso C, Foppa IM, Wikel S. Dermatologic Changes Induced by Repeated Ixodes scapularis Bites and Implications for Prevention of Tick-Borne Infection. Vector-Borne And Zoonotic Diseases 2009, 9: 603-610. PMID: 19196014, PMCID: PMC2883515, DOI: 10.1089/vbz.2008.0091.Peer-Reviewed Original ResearchConceptsBALB/c miceVascular dilatationInflammatory cellsC miceSkin biopsiesTick-borne pathogen transmissionI. scapularis nymphsTick attachmentScapularis nymphsSimilar histologic patternTick-Borne InfectionsMechanism of preventionBorrelia burgdorferi transmissionDermatologic changesHistologic patternTick exposureBite siteImmune hostHistopathologic reactionsTick-borne pathogensPathogen transmissionTick immunityCellular changesMiceMarked increase