Assessment of Clonality in Cutaneous Lymphoid Infiltrates by Polymerase Chain Reaction Analysis of Immunoglobulin Heavy Chain Gene Rearrangement
Ritter J, Wick M, Adesokan P, Fitzgibbon J, Zhu X, Humphrey P. Assessment of Clonality in Cutaneous Lymphoid Infiltrates by Polymerase Chain Reaction Analysis of Immunoglobulin Heavy Chain Gene Rearrangement. American Journal Of Clinical Pathology 1997, 108: 60-68. PMID: 9208979, DOI: 10.1093/ajcp/108.1.60.Peer-Reviewed Original ResearchConceptsCutaneous lymphoid infiltratesPolymerase chain reactionLymphoid infiltratesMonoclonal bandImmunoglobulin heavy chain geneFalse-positive resultsT cellsCell lymphomaB cellsValue of PCRLarge cell casesSparse perivascular infiltrateImmunoglobulin heavy chain gene rearrangementMixed cell lymphomaLarge cell lymphomaB-cell immunophenotypeHeavy chain gene rearrangementHeavy chain geneAssessment of clonalityChain gene rearrangementPerivascular infiltratesClinical featuresPolymerase chain reaction analysisClinical findingsMixed lesions