Interobserver Reproducibility in the Diagnosis of Prostatic Intraepithelial Neoplasia
Epstein J, Grignon D, Humphrey P, McNeal J, Sesterhenn I, Troncoso P, Wheeler T. Interobserver Reproducibility in the Diagnosis of Prostatic Intraepithelial Neoplasia. The American Journal Of Surgical Pathology 1995, 19: 873-886. PMID: 7611534, DOI: 10.1097/00000478-199508000-00002.Peer-Reviewed Original ResearchConceptsHigh-grade PINLow-grade PINInterobserver reproducibilityProstatic intraepithelial neoplasiaSmall atypical glandsBenign prostate tissueIntraepithelial neoplasiaSame histologyAtypical glandsBiopsy materialProminent nucleoliUniform diagnosisCribriform glandsProstate tissueCancerLesionsLevel of agreementDiagnostic issuesUniform agreementPathologistsGlandDiagnosisConsecutive examplesBiopsyGroup