Identification of genetic variations in Necator americanus through resequencing by whole genome amplification
Liu Y, Liu H, Xie Y, Zhang B, Zou X, Ou M, Ye X, Han Y, Wu J, Chen X, Dong S, Zhu K, Guo C, Wang P, Zhai H, Jing C, Yang G. Identification of genetic variations in Necator americanus through resequencing by whole genome amplification. Journal Of International Medical Research 2019, 47: 4353-4364. PMID: 31331217, PMCID: PMC6753555, DOI: 10.1177/0300060519862069.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsFemaleGene AmplificationGene OntologyGenetic VariationHumansMiddle AgedMolecular Sequence AnnotationNecator americanusPolymorphism, Single NucleotideWhole Genome SequencingConceptsWhole-genome resequencingSingle nucleotide polymorphismsGenome resequencingGenetic variationParasite genome sequencesDe novo genome assemblyMost single nucleotide polymorphismsGene ontology analysisNovo genome assemblyMultiple displacement amplification (MDA) methodCommon drug targetsWhole genome amplificationGenome assemblyOntology analysisReference genomeGenome sequenceGO analysisSequencing readsDrug targetsGenome amplificationSmall parasitesNucleotide polymorphismsParasite samplesGenotype probabilitiesResequencing