Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications
Cui C, Shu W, Li P. Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications. Frontiers In Cell And Developmental Biology 2016, 4: 89. PMID: 27656642, PMCID: PMC5011256, DOI: 10.3389/fcell.2016.00089.Peer-Reviewed Original ResearchSingle-molecule RNA FISHSingle nucleotide polymorphism (SNP) lociSingle gene levelSingle-copy sequencesGene-specific probesSingle-cell DNASitu hybridizationSingle cellsChromosomal organizationRNA FISHGenomic organizationTranscriptional dynamicsGenomic structurePhysical mapping toolChromosome haplotypesRepetitive sequencesRNA transcriptionMultiple genesBiological processesPolymorphism lociFISH technologyCombinatorial labelingGene levelMicrodeletion/microduplication syndromesLiving cells