Long-Term Use of GLP-1 Receptor Agonists Alter GLP-1 Receptor mRNA Expression in Hindbrain Pathways That Regulate Gastric Motility in Mice
WANG P, MAMILLAPALLI R, ZHU W, CHAN O. Long-Term Use of GLP-1 Receptor Agonists Alter GLP-1 Receptor mRNA Expression in Hindbrain Pathways That Regulate Gastric Motility in Mice. Diabetes 2018, 67 DOI: 10.2337/db18-1088-p.Peer-Reviewed Original ResearchGLP-1R expressionGLP-1R mRNA expressionGastric motilityGLP-1RAsMRNA expressionGLP-1 receptor mRNA expressionSuppressive effectGLP-1 receptor agonistsPost-prandial glucose levelsType 2 diabetesReceptor mRNA expressionAdeno-associated viral vectorLong-term useHindbrain pathwaysIncretin systemSolitary tractGlucagon releaseReceptor agonistC57BL6 micePretreatment levelsGLP-1RGlucose levelsTherapeutic strategiesReceptor desensitizationGLP-1R.