2008
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
Liang J, Wan M, Zhang Y, Gu P, Xin H, Jung SY, Qin J, Wong J, Cooney AJ, Liu D, Songyang Z. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nature Cell Biology 2008, 10: 731-739. PMID: 18454139, DOI: 10.1038/ncb1736.Peer-Reviewed Original ResearchConceptsES cell fateRepression complexMouse ES cellsCell fateTranscription factorsES cellsTranscriptional repression complexES cell differentiationEssential transcription factorEmbryonic stem cellsSub-stoichiometric levelsHistone deacetylase activityNuRD complexRepressor complexEndogenous NanogProtein complexesGene transcriptionTarget genesDeacetylase activityNanogNuRDGenesStem cellsCellsComplexes
2003
Expression of the Orphan Nuclear Receptor, Germ Cell Nuclear Factor, in Mouse Gonads and Preimplantation Embryos1
Lan ZJ, Gu P, Xu X, Cooney AJ. Expression of the Orphan Nuclear Receptor, Germ Cell Nuclear Factor, in Mouse Gonads and Preimplantation Embryos1. Biology Of Reproduction 2003, 68: 282-289. PMID: 12493724, DOI: 10.1095/biolreprod.102.008151.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibody SpecificityBase SequenceBlastocystDNADNA-Binding ProteinsFemaleGene Expression Regulation, DevelopmentalImmunohistochemistryIn Vitro TechniquesMaleMiceMice, Inbred C57BLMolecular Sequence DataNuclear Receptor Subfamily 6, Group A, Member 1OocytesOogenesisOvaryPregnancyReceptors, Cytoplasmic and NuclearSpermatogenesisSpermatozoaTestisConceptsGerm cell nuclear factorGCNF proteinMouse gonadsEmbryonic developmentZygotic gene expressionNormal mouse embryonic developmentNuclear receptorsMouse embryonic developmentPreimplantation embryonic developmentSpermatogenic cellsPostmeiotic spermatogenic cellsCytoplasm of oocytesOrphan nuclear receptorNuclear factorPreimplantation Embryos1Early embryosGene transcriptionMaternal proteinsOrphan memberMouse embryosGene expressionPreimplantation embryosGCNFProteinEmbryos