Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders
Morshed S, Parveen S, Leckman J, Mercadante M, Kiss M, Miguel E, Arman A, Yazgan Y, Fujii T, Paul S, Peterson B, Zhang H, King R, Scahill L, Lombroso P. Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders. Biological Psychiatry 2001, 50: 566-577. PMID: 11690591, DOI: 10.1016/s0006-3223(01)01096-4.Peer-Reviewed Original ResearchConceptsTotal antinuclear antibodiesAntinuclear antibodiesAutoimmune disordersTourette syndromeAnticytoskeletal antibodiesAntineural antibodiesStreptococcal infectionT patientsTS patientsBeta-hemolytic streptococcal infectionPrior streptococcal infectionHemolytic streptococcal infectionAntistreptolysin O titerIndirect immunofluorescent assayLevels of immunoreactivityWestern blot techniqueMean rankClinical characteristicsSydenham's choreaO titerPatient groupSC patientsIgG antibodiesIgG classNormal controlsGenetics of Childhood Disorders: XXX. Autoimmune Disorders, Part 3: Myasthenia Gravis and Rasmussen's Encephalitis
LOMBROSO P, MERCADANTE M, Lombroso P. Genetics of Childhood Disorders: XXX. Autoimmune Disorders, Part 3: Myasthenia Gravis and Rasmussen's Encephalitis. Journal Of The American Academy Of Child & Adolescent Psychiatry 2001, 40: 1115-1117. PMID: 11556637, DOI: 10.1097/00004583-200109000-00022.Peer-Reviewed Original Research