2022
Prevalence and Management of Invasive Bacterial Infections in Febrile Infants Ages 2 to 6 Months
Green R, Sartori L, Lee B, Linn A, Samuels M, Florin T, Aronson P, Chamberlain J, Michelson K, Nigrovic L. Prevalence and Management of Invasive Bacterial Infections in Febrile Infants Ages 2 to 6 Months. Annals Of Emergency Medicine 2022, 80: 499-506. PMID: 35940993, DOI: 10.1016/j.annemergmed.2022.06.014.Peer-Reviewed Original ResearchConceptsInvasive bacterial infectionsCase-control studyBacterial infectionsFebrile infantsInfants 2Emergency departmentEligible patient encountersOlder febrile infantsCerebrospinal fluid culturesInfection prevalenceAge-matched infantsEvidence-based guidelinesInfants ages 2Months of ageLow-value testingFebrile neonatesOverall cohortRetrospective cohortSecondary outcomesPrimary outcomeAntibiotic administrationBacterial cultureFluid cultureCerebrospinal fluidLower risk
2017
Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger
Aronson PL, Lyons TW, Cruz AT, Freedman SB, Okada PJ, Fleming AH, Arms JL, Thompson AD, Schmidt SM, Louie J, Alfonzo MJ, Monuteaux MC, Nigrovic LE, Group P, Alpern E, Balamuth F, Bradin S, Curtis S, Garro A, Grether-Jones K, Ishimine P, Kulik D, Mahajan P, Miller A, Mistry R, Pruitt C, Schnadower D, Shah S, Thomson J, Uspal N. Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger. The Journal Of Pediatrics 2017, 189: 169-174.e2. PMID: 28705656, PMCID: PMC5870831, DOI: 10.1016/j.jpeds.2017.06.021.Peer-Reviewed Original ResearchConceptsPCR testShorter LOSCentral nervous system infectionPolymerase chain reaction testingCerebrospinal fluid culturesNervous system infectionPlanned secondary analysisLarge multicenter cohortCerebrospinal fluid evaluationLength of stayPositive test resultsNegative test resultsDays of ageHospital lengthHospital LOSRetrospective cohortSystem infectionBacterial meningitisMulticenter cohortPatient ageFluid cultureHospital CenterPCR testingReaction testingInfants