2009
The Association between Cocaine Use and Treatment Outcomes in Patients Receiving Office‐Based Buprenorphine/Naloxone for the Treatment of Opioid Dependence
Sullivan LE, Moore BA, O'Connor PG, Barry DT, Chawarski MC, Schottenfeld RS, Fiellin DA. The Association between Cocaine Use and Treatment Outcomes in Patients Receiving Office‐Based Buprenorphine/Naloxone for the Treatment of Opioid Dependence. American Journal On Addictions 2009, 19: 53-58. PMID: 20132122, PMCID: PMC3107713, DOI: 10.1111/j.1521-0391.2009.00003.x.Peer-Reviewed Original ResearchConceptsOpioid-negative urinesBuprenorphine/naloxoneUrine toxicology testsWeeks of treatmentWorse treatment outcomesTreatment outcomesCocaine useTreatment retentionMean weekBuprenorphine/naloxone maintenanceGreater percentageToxicology testsUrine toxicology resultsOpioid dependenceToxicology resultsPatientsTargeted interventionsWeeksNaloxoneOutcomesTreatmentBaselineUrineAssociationPercentage
1999
Plasma concentrations of buprenorphine 24 to 72 hours after dosing
Chawarski MC, Schottenfeld RS, O’Connor P, Pakes J. Plasma concentrations of buprenorphine 24 to 72 hours after dosing. Drug And Alcohol Dependence 1999, 55: 157-163. PMID: 10402160, DOI: 10.1016/s0376-8716(98)00192-6.Peer-Reviewed Original ResearchConceptsDose scheduleWithdrawal symptomsPlasma concentrationsDaily buprenorphine doseHigh-dose scheduleThrice-weekly scheduleAdministration of buprenorphineOpiate-dependent subjectsHigher plasma concentrationsUse of heroinBuprenorphine doseDaily administrationOutpatient clinicPlasma levelsSublingual administrationAgonist effectsOpiate useHeroin useLow doseHigh doseBuprenorphine solutionMg/70High dosesConcentration 24Dependent subjects
1997
PHARMACOTHERAPY FOR OPIOID AND COCAINE ABUSE
Warner E, Kosten T, O'Connor P. PHARMACOTHERAPY FOR OPIOID AND COCAINE ABUSE. Medical Clinics Of North America 1997, 81: 909-925. PMID: 9222260, DOI: 10.1016/s0025-7125(05)70555-1.Peer-Reviewed Original Research
1994
HIV infection and cocaine use in methadone maintained and untreated intravenous drug users
Meandzija B, O'Connor P, Fitzgerald B, Rounsaville B, Kosten T. HIV infection and cocaine use in methadone maintained and untreated intravenous drug users. Drug And Alcohol Dependence 1994, 36: 109-113. PMID: 7851277, DOI: 10.1016/0376-8716(94)90092-2.Peer-Reviewed Original ResearchConceptsIntravenous drug usersMethadone maintenance treatmentMethadone maintenance programHIV infectionCocaine useMore cocaine useMaintenance treatmentRisk factorsDrug usersMethadone maintenance treatment groupHuman immunodeficiency virus (HIV) transmissionAfrican AmericansMaintenance treatment groupNon-infected subjectsInjection frequencyHIV-negativeHIV testingDrug injectionStratified analysisTreatment groupsTotal cocaineHIVRisk behaviorsGreater riskInfection