2007
Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction.
Martell BA, O'Connor PG, Kerns RD, Becker WC, Morales KH, Kosten TR, Fiellin DA. Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Annals Of Internal Medicine 2007, 146: 116-27. PMID: 17227935, DOI: 10.7326/0003-4819-146-2-200701160-00006.Peer-Reviewed Original ResearchConceptsChronic back painSubstance use disordersEfficacy of opioidsBack painMedication-taking behaviorUse disordersOpioid treatmentOpioid medicationsStudy qualityShort-term pain reliefCurrent substance use disorderCochrane Central RegisterLifetime substance use disorderControlled Clinical TrialsLong-term efficacyPoor study qualityEnglish-language studiesTransdermal opioidsOpioid prescribingPain reliefCentral RegisterDifferent opioidsReduced painClinical trialsNonsignificant reduction
2002
New federal initiatives to enhance the medical treatment of opioid dependence.
Fiellin DA, O'Connor PG. New federal initiatives to enhance the medical treatment of opioid dependence. Annals Of Internal Medicine 2002, 137: 688-92. PMID: 12379070, DOI: 10.7326/0003-4819-137-8-200210150-00014.Peer-Reviewed Original ResearchConceptsOpioid dependenceMedical treatmentOpioid agonist medicationsRole of internistsAgonist medicationsPharmacologic treatmentMaintenance treatmentNew medicationsMedical conditionsOffice settingSubstantial healthMedicationsPatientsTreatmentInternistsRecent federal initiativesFederal initiativesNew federal initiativesComplicationsCare