2022
Anemia in the pediatric patient
Gallagher PG. Anemia in the pediatric patient. Blood 2022, 140: 571-593. PMID: 35213686, PMCID: PMC9373018, DOI: 10.1182/blood.2020006479.Peer-Reviewed Original ResearchConceptsLow birth weightIron deficiency anemiaNovel pharmacologic agentsWorld Health OrganizationNeurologic complicationsHeart failurePediatric patientsPhysical examinationBirth weightDeficiency anemiaChronic diseasesNutritional anemiaPharmacologic agentsSyndromic causesUndiagnosed casesTreatment strategiesCommon causeFamily historyPopulation-based approachAnemiaImportant causePreschool-age childrenDiagnostic testingGenetic testingDysmorphic featuresHMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation
Dulmovits BM, Tang Y, Papoin J, He M, Li J, Yang H, Addorisio ME, Kennedy L, Khan M, Brindley E, Ashley RJ, Ackert-Bicknell C, Hale J, Kurita R, Nakamura Y, Diamond B, Barnes BJ, Hermine O, Gallagher PG, Steiner LA, Lipton JM, Taylor N, Mohandas N, Andersson U, Al-Abed Y, Tracey KJ, Blanc L. HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation. Blood 2022, 139: 3181-3193. PMID: 35040907, PMCID: PMC9136881, DOI: 10.1182/blood.2021012048.Peer-Reviewed Original ResearchConceptsAnemia of inflammationDamage-associated molecular pattern moleculesHigh-mobility group box 1 proteinMobility group box 1 proteinErythroid precursorsGroup box 1 proteinAdvanced glycation end productsAnti-HMGB1 antibodyGlycation end productsMolecular pattern moleculesChronic phaseSepsis onsetChronic diseasesHMGB1 receptorsAnemia developmentPattern moleculesAnemiaGenetic ablationInflammationMurine precursorRefractory stateHMGB1Reduced expansionEPO signalingDeleterious effects
2018
A Ser725Arg mutation in Band 3 abolishes transport function and leads to anemia and renal tubular acidosis
Yang E, Seo-Mayer P, Lezon-Geyda K, Badior KE, Li J, Casey JR, Reithmeier RAF, Gallagher PG. A Ser725Arg mutation in Band 3 abolishes transport function and leads to anemia and renal tubular acidosis. Blood 2018, 131: 1759-1763. PMID: 29483102, PMCID: PMC5897869, DOI: 10.1182/blood-2018-01-827725.Peer-Reviewed Original Research
2007
Erythrocyte Disorders in the Perinatal Period
Steiner LA, Gallagher PG. Erythrocyte Disorders in the Perinatal Period. Seminars In Perinatology 2007, 31: 254-261. PMID: 17825683, PMCID: PMC2098040, DOI: 10.1053/j.semperi.2007.05.003.Peer-Reviewed Original Research