2010
A Fused α-β “Mini-spectrin” Mimics the Intact Erythrocyte Spectrin Head-to-head Tetramer*
Harper SL, Li D, Maksimova Y, Gallagher PG, Speicher DW. A Fused α-β “Mini-spectrin” Mimics the Intact Erythrocyte Spectrin Head-to-head Tetramer*. Journal Of Biological Chemistry 2010, 285: 11003-11012. PMID: 20139081, PMCID: PMC2856305, DOI: 10.1074/jbc.m109.083048.Peer-Reviewed Original ResearchConceptsN-terminal regionFull-length dimerC-terminal regionRed cell membrane integrityGel filtration analysisLateral associationCell membrane integrityOligomeric stateFusion proteinAlpha-spectrinTetramer formationBeta subunitC-terminalN-terminalConformational statesFunctional studiesFiltration analysisMembrane integritySpectrin heterodimersTerminal peptidesDimer interactionsDistinct groupsSpectrinSpectrin dimersProtein
2001
Spectrin Oligomerization is Cooperatively Coupled to Membrane Assembly: A Linkage Targeted by Many Hereditary Hemolytic Anemias?
Giorgi M, Cianci C, Gallagher P, Morrow J. Spectrin Oligomerization is Cooperatively Coupled to Membrane Assembly: A Linkage Targeted by Many Hereditary Hemolytic Anemias? Experimental And Molecular Pathology 2001, 70: 215-230. PMID: 11418000, DOI: 10.1006/exmp.2001.2377.Peer-Reviewed Original Research