2008
Matched Case-Control Analysis of Polymicrobial Bloodstream Infection In A Neonatal Intensive Care Unit
Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. Matched Case-Control Analysis of Polymicrobial Bloodstream Infection In A Neonatal Intensive Care Unit. Infection Control And Hospital Epidemiology 2008, 29: 914-920. PMID: 18808341, DOI: 10.1086/591323.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaCase-Control StudiesFemaleFungemiaFungiGram-Negative BacteriaGram-Negative Bacterial InfectionsGram-Positive BacteriaGram-Positive Bacterial InfectionsHumansIncidenceInfant, Low Birth WeightInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Very Low Birth WeightIntensive Care Units, NeonatalMaleRisk FactorsConceptsPolymicrobial bloodstream infectionsMonomicrobial bloodstream infectionSevere underlying conditionsBloodstream infectionsOnset of infectionUnderlying conditionRisk factorsMultivariate analysisIndwelling central venous catheterIntensive care unit patientsNeonatal intensive care unitMatched Case-Control AnalysisIndependent risk factorNewborn intensive care unit (NICU) patientsCare unit patientsCentral venous cathetersIntensive care unitNeonatal bloodstream infectionsMost risk factorsCase-control studyCase-control analysisCoagulase-negative staphylococciHospital NICUUnit patientsVenous cathetersAnkyrin‐linked hereditary spherocytosis in an African–American kindred
Sangerman J, Maksimova Y, Edelman EJ, Morrow JS, Forget BG, Gallagher PG. Ankyrin‐linked hereditary spherocytosis in an African–American kindred. American Journal Of Hematology 2008, 83: 789-794. PMID: 18704959, PMCID: PMC11304496, DOI: 10.1002/ajh.21254.Peer-Reviewed Original ResearchConceptsInitiator methionineNull allelesErythrocyte membrane protein genesMembrane protein geneRabbit reticulocyte lysateTissue-specific promotersErythrocyte membrane skeletonExon 1 sequencesIsoform diversityAlternative splicingTranslation initiationProtein geneAnkyrin geneMembrane skeletonAlternate polyadenylationPlasma membraneReticulocyte lysateMethionine mutationCOOH terminusErythroid cellsDownstream codonsGenomic DNANumerous isoformsAnkyrinGenes
2007
Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unit
Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unit. Archives Of Disease In Childhood Fetal & Neonatal 2007, 92: f120. PMID: 17088342, PMCID: PMC2675455, DOI: 10.1136/adc.2006.102855.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaBirth WeightCase-Control StudiesConnecticutCross InfectionDrug Resistance, BacterialEndemic DiseasesEscherichia coliEscherichia coli InfectionsFemaleHumansInfant, NewbornIntensive Care Units, NeonatalMaleMicrobial Sensitivity TestsPrognosisRisk FactorsSerratia InfectionsSerratia marcescensConceptsNeonatal intensive care unitIntensive care unitCare unitUninfected controlsHospital Neonatal Intensive Care UnitSerratia marcescens bacteremiaMedian gestational ageCentral vascular catheterEscherichia coli bacteremiaRecords of infantsCase-control studyHigher overall mortalityE coliOnset of infectionCase-control analysisTime of infectionHigh rateAssociated meningitisHospital courseColi bacteremiaOverall mortalityGestational agePremature infantsVascular cathetersBirth weight
2003
Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis
Gallagher PG, Chang SH, Rettig MP, Neely JE, Hillery CA, Smith BD, Low PS. Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis. Blood 2003, 101: 4625-4627. PMID: 12560240, DOI: 10.1182/blood-2001-12-0329.Peer-Reviewed Original ResearchConceptsMechanism of thrombosisErythrocyte filtration rateSickle cell diseaseAdherence of erythrocytesMembrane phospholipid asymmetryAdhesion of erythrocytesFiltration rateHealthy controlsCell diseaseUncommon variantEndothelial adherenceMild increaseThrombosisPatientsEndothelial monolayersPhosphatidylserine exposureErythrocytesPhospholipid asymmetryAdherenceHereditary stomatocytosisDisease