2015
Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program
Nelson MU, Bizzarro MJ, Baltimore RS, Dembry LM, Gallagher PG. Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program. Journal Of Clinical Microbiology 2015, 53: 2492-2501. PMID: 26019206, PMCID: PMC4508396, DOI: 10.1128/jcm.00470-15.Peer-Reviewed Original ResearchMeSH KeywordsDNA, BacterialEpidemiological MonitoringFemaleGenetic VariationGenotypeGenotyping TechniquesHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMethicillin-Resistant Staphylococcus aureusMolecular EpidemiologyMolecular TypingRetrospective StudiesStaphylococcal InfectionsVirulence FactorsConceptsNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusIntensive care unitMRSA colonizationMolecular epidemiologyCare unitStaphylococcal cassette chromosome mec type IIAccessory gene regulator (agr) groupsMRSA colonization rateToxic shock syndrome toxinAgr group 1Exfoliative toxin AStaphylococcus aureusPotential virulence factor genesVirulence factor genesMRSA infectionSignificant morbidityClinical differencesPatient daysPulsed-field gel electrophoresisToxin AUSA300 strainGroup 1Continued vigilanceInfection
2014
Methicillin-resistant Staphylococcus aureus : impact on care in the neonatal unit
Nelson M, Bizzarro M, Gallagher P. Methicillin-resistant Staphylococcus aureus : impact on care in the neonatal unit. 2014, 41-61. DOI: 10.2217/ebo.13.571.Peer-Reviewed Original ResearchNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusMRSA transmissionTreatment of MRSAIntensive care unitAppropriate treatment regimensMRSA colonizationNeonatal morbidityMRSA acquisitionCare unitIll infantsNeonatal unitSignificant morbidityTreatment regimensRisk factorsMRSA strainsPrevention strategiesNeonatesInfectionPervasive pathogenEarly detectionMorbidityStaphylococcus aureusInfantsEpidemiology
2012
Methicillin-Resistant Staphylococcus aureus in the Neonatal Intensive Care Unit
Nelson MU, Gallagher PG. Methicillin-Resistant Staphylococcus aureus in the Neonatal Intensive Care Unit. Seminars In Perinatology 2012, 36: 424-430. PMID: 23177801, PMCID: PMC3508470, DOI: 10.1053/j.semperi.2012.06.004.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial Physiological PhenomenaClinical ProtocolsCommunity-Acquired InfectionsCost of IllnessCross InfectionHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfection ControlIntensive Care Units, NeonatalMethicillin-Resistant Staphylococcus aureusPrevalenceRisk FactorsStaphylococcal InfectionsConceptsNeonatal intensive care unitMethicillin-resistant Staphylococcus aureusIntensive care unitCare unitCharacteristics of MRSAStaphylococcus aureusCertain infantsMRSA infectionNICU populationIll infantsRisk factorsEpidemiologic assessmentClinical interventionsInfectionFrequent sourceInfantsTransmission patternsInterventionAureusMolecular analysisAdditional factorsMorbidityNeonatesNumerous strategiesPrevention
2007
Antibiotic-Resistant Organisms in the Neonatal Intensive Care Unit
Bizzarro MJ, Gallagher PG. Antibiotic-Resistant Organisms in the Neonatal Intensive Care Unit. Seminars In Perinatology 2007, 31: 26-32. PMID: 17317424, DOI: 10.1053/j.semperi.2007.01.004.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitIntensive care unitCare unitMultidrug-resistant Gram-negative rodsStandard antimicrobial therapyMethicillin-resistant Staphylococcus aureusProper hand hygieneVancomycin-resistant EnterococcusAntibiotic-resistant organismsEmpiric treatmentProlonged courseUse of antimicrobialsAntimicrobial therapyAntibiotic exposureHand hygieneDecolonization strategiesGram-negative rodsResistant organismsBacterial infectionsStaphylococcus aureusBacterial acquisitionPotential reservoirsAntimicrobialsCohortingNeonates