2014
Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes*
Bagriantsev SN, Gracheva EO, Gallagher PG. Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes*. Journal Of Biological Chemistry 2014, 289: 31673-31681. PMID: 25305018, PMCID: PMC4231648, DOI: 10.1074/jbc.r114.612697.Peer-Reviewed Original ResearchConceptsPiezo proteinsCellular processesMammalian cellsCellular developmentMechanosensory transductionCellular migrationIon channelsHereditary xerocytosisVolume regulationProteinBiologic processesRegulationImportant insightsTransductionMechanosensationRegulatorMutationsXerocytosisProliferationCellsMechanoVariety of disordersElongationMigrationProminent feature
2013
Disorders of red cell volume regulation
Gallagher PG. Disorders of red cell volume regulation. Current Opinion In Hematology 2013, 20: 201-207. PMID: 23519154, DOI: 10.1097/moh.0b013e32835f6870.Peer-Reviewed Original ResearchConceptsVolume regulationCassette family memberErythrocyte volume homeostasisErythrocyte hydrationCell volume regulationMechanosensory proteinsGenetic basisSolute homeostasisMechanotransduction pathwaysGlucose transporterNew therapeutic targetsErythrocyte volume regulationNovel mechanismCellular waterCellular dehydrationRecent insightsCellular volumeHomeostasisRegulationAnion transportersTherapeutic targetTransportersPathwayVolume homeostasisRecent studies
2009
Sites of Regulated Phosphorylation that Control K-Cl Cotransporter Activity
Rinehart J, Maksimova Y, Tanis J, Stone K, Hodson C, Zhang J, Risinger M, Pan W, Wu D, Colangelo C, Forbush B, Joiner C, Gulcicek E, Gallagher P, Lifton R. Sites of Regulated Phosphorylation that Control K-Cl Cotransporter Activity. Journal Of End-to-End-testing 2009, 138: 525-536. DOI: 10.1016/s9999-9994(09)20441-7.Peer-Reviewed Original ResearchIntrinsic transport activityK-Cl cotransporterTransport activityCell volume regulationRegulated phosphorylationRNA interferenceAlanine substitutionsCultured cellsHomologous sitesKCC activityWNK1 expressionNeonatal mouse brainVolume regulationNeuronal functionHypotonic conditionsActive cotransportPhosphorylationIntracellular chloride concentrationCotransporter activityKCC3Human red blood cellsKCC2 activationFundamental roleMouse brainRegulation