Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes
Li X, Wang S, Li Y, Deng C, Steiner LA, Xiao H, Wu C, Bungert J, Gallagher PG, Felsenfeld G, Qiu Y, Huang S. Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes. Blood 2011, 118: 1386-1394. PMID: 21653943, PMCID: PMC3152501, DOI: 10.1182/blood-2010-11-319111.Peer-Reviewed Original ResearchConceptsErythroid genesInsulator sitesBarrier activityActive chromatin structureNucleosome remodeling activitiesChromatin barrier activityHistone H3K4 methyltransferaseChicken β-globinChromatin boundariesNURF complexChromatin structureInsulator functionNucleosome positioningMultiprotein complexesProtein complexesH3K4 methyltransferaseHS4 insulatorChromatin insulatorNURFH3K27me3 levelsLoci resultsLinker regionKnock-downΒ-globinFunctional collaboration