2014
Cytogenomic mapping and bioinformatic mining reveal interacting brain expressed genes for intellectual disability
Xu F, Li L, Schulz VP, Gallagher PG, Xiang B, Zhao H, Li P. Cytogenomic mapping and bioinformatic mining reveal interacting brain expressed genes for intellectual disability. Molecular Cytogenetics 2014, 7: 4. PMID: 24410907, PMCID: PMC3905969, DOI: 10.1186/1755-8166-7-4.Peer-Reviewed Original ResearchBrain-expressed genesIngenuity Pathway AnalysisArray comparative genomic hybridizationCentral nervous system-specific genesNervous system-specific genesChromosomal imbalancesGene expression regulationSignificant gene networksTissue expression patternsOligonucleotide array comparative genomic hybridizationChromosomal structural rearrangementsExpression regulationFunctional annotationGene networksGene relationshipsEnsembl ResourcesComparative genomic hybridizationCell signalingIntegrated DiscoveryCellular assemblyBioinformatics miningSpecific genesCandidate genesExpression patternsGenomic disorders
2005
Multiple isoforms of the KC1 cotransporter are expressed in sickle and normal erythroid cells
Crable SC, Hammond SM, Papes R, Rettig RK, Zhou GP, Gallagher PG, Joiner CH, Anderson KP. Multiple isoforms of the KC1 cotransporter are expressed in sickle and normal erythroid cells. Experimental Hematology 2005, 33: 624-631. PMID: 15911086, DOI: 10.1016/j.exphem.2005.02.006.Peer-Reviewed Original ResearchConceptsErythroid cellsKCC isoformsMultiple isoformsSplicing variantsStructure/function studiesKCl cotransporterWild-type cellsHuman erythroid cellsDifferentiated erythroid precursorsCl-dependent K fluxTransient transfection experimentsNormal erythroid cellsIsoform expression patternCotransporter activityRed cellsKCC genesExpression patternsReticulocyte maturationHuman red cellsKCC1 geneTransfection experimentsReverse transcriptase-PCRSplice variantsRelative abundanceGenes