2007
A GC Box Element Is Critical for Transcriptional Regulation of the K-Cl Cotransporter Isoform KCC3a in Hematopoetic Cells.
Crable S, Joiner C, Gallagher P. A GC Box Element Is Critical for Transcriptional Regulation of the K-Cl Cotransporter Isoform KCC3a in Hematopoetic Cells. Blood 2007, 110: 1712. DOI: 10.1182/blood.v110.11.1712.1712.Peer-Reviewed Original ResearchUntranslated sequenceInitiator methionineErythroid cellsNovel transcriptsPromoter activityExon 1Cell RNATerminal truncationExon 1DTrans-regulatory factorsMajor splicing isoformsPotential phosphorylation sitesErythroid K562 cellsGC-box elementsFull promoter activityPrimer extension analysisTranslation initiation siteLate erythroid cellsFurther deletion analysisVolume regulationKCl cotransporterLuciferase promoter constructsBone marrow RNATranscriptional regulationEST database
2006
Alternative Splicing within Exon 1 of the KCl Cotransporter-3 (KCC3) Gene Results in Novel Transcripts in Erythroid Cells.
Joiner C, Crable S, Gallagher P. Alternative Splicing within Exon 1 of the KCl Cotransporter-3 (KCC3) Gene Results in Novel Transcripts in Erythroid Cells. Blood 2006, 108: 1564. DOI: 10.1182/blood.v108.11.1564.1564.Peer-Reviewed Original ResearchUntranslated sequenceNovel transcriptsInitiator methionineErythroid cellsAlternative splicingPromoter activityExon 1Cell RNATerminal truncationPotential phosphorylation sitesMajor splicing isoformsErythroid K562 cellsPrimer extension analysisTranslation initiation siteVolume regulationNegative regulatory elementKCl cotransporterLuciferase promoter constructsBone marrow RNAEST databaseTranscriptional controlGenomic regionsPhosphorylation sitesSplicing isoformsDifferent transcripts