2005
A Differentiation Block in Erythroid Cells Lacking Erythroid Krupple-Like Factor (EKLF).
Gallagher P, Arcasoy M, Vayda S, Dressman H, Bieker J, Bodine D. A Differentiation Block in Erythroid Cells Lacking Erythroid Krupple-Like Factor (EKLF). Blood 2005, 106: 526. DOI: 10.1182/blood.v106.11.526.526.Peer-Reviewed Original ResearchWild typeErythroid differentiationMicroarray analysisDifferentiation blockErythroid cellsFocus genesMouse Genome 430 2.0 ArrayAffymetrix GeneChip Mouse Genome 430 2.0 ArrayFetal liver cellsCell cycle defectsTerminal erythroid differentiationCell cycle controlFetal liverIngenuity Pathway AnalysisR2 cellsMature erythroid cellsΒ-globin geneErythroid progenitor cellsErythroid genesNumerous genesDefinitive erythropoiesisDNA replicationTranscription factorsΒ-spectrinBiological functions
2004
Multiple Defects in Erythroid Gene Expression in Erythroid Krupple-Like Factor (EKLF) Target Genes in EKLF-Deficient Mice.
Gallagher P, Pilon A, Arcasoy M, Bodine D. Multiple Defects in Erythroid Gene Expression in Erythroid Krupple-Like Factor (EKLF) Target Genes in EKLF-Deficient Mice. Blood 2004, 104: 1602. DOI: 10.1182/blood.v104.11.1602.1602.Peer-Reviewed Original ResearchDNaseI hypersensitive sitesSubtractive hybridizationHypersensitive sitesΒ-globin geneHistone H3Transcription factorsTarget genesFetal liver cellsΒ-spectrinGene expressionΒ-globinErythroid gene expressionMouse Genome 430 2.0 ArrayAffymetrix GeneChip Mouse Genome 430 2.0 ArrayFactor target genesAHSP gene expressionChromatin immunoprecipitation analysisBand 3Mature erythroid progenitorsAHSP promoterRBC membrane proteinsErythroid genesChromatin upstreamChromatin modulatorsRegulated genes