1992
Luminal flow rate regulates proximal tubule H-HCO3 transporters
Preisig P. Luminal flow rate regulates proximal tubule H-HCO3 transporters. American Journal Of Physiology 1992, 262: f47-f54. PMID: 1310229, DOI: 10.1152/ajprenal.1992.262.1.f47.Peer-Reviewed Original ResearchConceptsLuminal flow rateLuminal perfusateNa-H antiporter activityProximal tubule acidificationProgressive increaseRate-dependent changesNa-H antiporterTubule acidificationVivo microperfusionH secretionLuminal amilorideAcid loadSecretory activityAlkali loadPerfusateSensitive indexSymporter activityDisulfonic acidAntiporter activityMinBase transportActivityMicroperfusionInitial rateSecretion
1989
Contributions of cellular leak pathways to net NaHCO3 and NaCl absorption.
Preisig PA, Alpern RJ. Contributions of cellular leak pathways to net NaHCO3 and NaCl absorption. Journal Of Clinical Investigation 1989, 83: 1859-1867. PMID: 2542374, PMCID: PMC303906, DOI: 10.1172/jci114092.Peer-Reviewed Original Research
1988
Role of Na+-H+ antiport in rat proximal tubule NaCl absorption
Preisig P, Rector F. Role of Na+-H+ antiport in rat proximal tubule NaCl absorption. American Journal Of Physiology 1988, 255: f461-f465. PMID: 2843052, DOI: 10.1152/ajprenal.1988.255.3.f461.Peer-Reviewed Original ResearchConceptsChloride absorptionNaCl absorptionLuminal amilorideTransepithelial NaCl absorptionLate proximal tubuleRenal carbonic anhydrasePhysiological sodium concentrationProximal tubulesTubular fluidApical membraneNaCl cotransportSodium concentrationRatsNaCl uptakePotent inhibitorAmiloridePresent studyTubulesTight epitheliaInhibitorsAntiporter activityBase exchangePerfusateHydrochlorothiazideUptake
1987
Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption.
Preisig PA, Ives HE, Cragoe EJ, Alpern RJ, Rector FC. Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption. Journal Of Clinical Investigation 1987, 80: 970-978. PMID: 2888788, PMCID: PMC442334, DOI: 10.1172/jci113190.Peer-Reviewed Original Research