Controlled‐release oxycodone compared with controlled‐release morphine in the treatment of cancer pain: A randomized, double‐blind, parallel‐group study
Mucci‐LoRusso P, Berman B, Silberstein P, Citron M, Bressler L, Weinstein S, Kaiko R, Buckley B, Reder R. Controlled‐release oxycodone compared with controlled‐release morphine in the treatment of cancer pain: A randomized, double‐blind, parallel‐group study. European Journal Of Pain 1998, 2: 239-249. PMID: 15102384, DOI: 10.1016/s1090-3801(98)90020-9.Peer-Reviewed Original ResearchControlled-release morphineControlled-release oxycodoneCancer-related painVisual analogue scorePlasma concentrationsStable analgesiaPain intensityAdverse experiencesChronic cancer-related painControlled-release oral formulationsSevere cancer-related painSteady-state plasma concentrationsCancer pain patientsDouble-blind treatmentParallel-group studyLess itchingMorphine patientSuitable analgesicCancer painAnalogue scorePain controlSevere painCreatinine levelsTrough fluctuationOral formulation