1995
Comparative efficacy of DMP 840 against mouse and human solid tumor models
LoRusso P, Demchik L, Dan M, Polin L, Gross J, Corbett T. Comparative efficacy of DMP 840 against mouse and human solid tumor models. Investigational New Drugs 1995, 13: 195-203. PMID: 8729946, DOI: 10.1007/bf00873800.Peer-Reviewed Original ResearchConceptsMouse tumorsLarger body weight lossTumor cell linesTumor modelHighest non-toxic dosePhase I clinical trialHuman tumor xenograft modelsPhase II trialDMP 840Body weight lossHuman xenograft tumorsMouse solid tumorsNorth American centersHuman solid tumor modelsPhase II testingNon-toxic doseTumor xenograft modelCell linesP388/ADRSoft agar colony formationMouse tumor modelsSolid tumor modelsAgar colony formationII trialMouse tumor cell lines
1990
Activity of datelliptium acetate (NSC 311152; SR 95156A) against solid tumors of mice
Mucci-LoRusso P, Polin L, Biernat L, Valeriote F, Corbett T. Activity of datelliptium acetate (NSC 311152; SR 95156A) against solid tumors of mice. Investigational New Drugs 1990, 8: 253-261. PMID: 2177044, DOI: 10.1007/bf00171834.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAnimalsCarcinoma, Intraductal, NoninfiltratingColonic NeoplasmsDrug Screening Assays, AntitumorEllipticinesFemaleHumansInjections, IntravenousLeukemia L1210MaleMammary Neoplasms, ExperimentalMiceMice, Inbred StrainsNeoplasm TransplantationNeoplasms, ExperimentalPancreatic Neoplasms
1989
Activity of batracylin (NSC-320846) against solid tumors of mice
Mucci-LoRusso P, Polin L, Bissery M, Valeriote F, Plowman J, Luk G, Corbettv T. Activity of batracylin (NSC-320846) against solid tumors of mice. Investigational New Drugs 1989, 7: 295-306. PMID: 2557298, DOI: 10.1007/bf00173759.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAnimalsAntineoplastic AgentsCarcinoma, Intraductal, NoninfiltratingCell SurvivalCells, CulturedColonic NeoplasmsDrug Administration ScheduleDrug Screening Assays, AntitumorHumansMammary Neoplasms, ExperimentalMiceMice, Inbred StrainsNeoplasms, ExperimentalPancreatic NeoplasmsQuinazolinesTumor Cells, Cultured